SnO(2)-ZnSn(OH)(6): a novel binary affinity probe for global phosphopeptide detection.
SnO(2)-ZnSn(OH)(6): a novel binary affinity probe for global phosphopeptide detection.
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DOI：
10.1039/c3cc38909j
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发表时间：
2013-01
影响因子：
4.9
通讯作者：
Liping Li;Tao Zheng;Linnan Xu;Ze Li;Ling-Dong Sun;Z. Nie;Yu Bai;Huwei Liu
中科院分区：
文献类型：
--
作者：
Liping Li;Tao Zheng;Linnan Xu;Ze Li;Ling-Dong Sun;Z. Nie;Yu Bai;Huwei Liu
首次引入ZnSn（OH）（6）和SnO（2）-ZnSn（OH）（6）二元体系作为亲和探针用于磷酸肽的富集。提出了两种策略，即ZnSn（OH）（6）和SnO（2）串联富集或二元组分SnO（2）-ZnSn（OH）（6）在一次运行中富集，以增强多磷酸肽富集，并显着提高整体磷酸肽检测。
ZnSn(OH)(6) and binary-component SnO(2)-ZnSn(OH)(6) were introduced as affinity probes for phosphopeptide enrichment for the first time. Two strategies, either ZnSn(OH)(6) and SnO(2) serial enrichment or binary-component SnO(2)-ZnSn(OH)(6) enrichment in a single run, were proposed to enhance multi-phosphopeptide enrichment and to significantly improve global phosphopeptide detection.