Brain activations during conscious self-monitoring of speech production with delayed auditory feedback: An fMRI study
Brain activations during conscious self-monitoring of speech production with delayed auditory feedback: An fMRI study
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DOI：
10.1002/hbm.10119
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发表时间：
2003-09-01
影响因子：
4.8
通讯作者：
Sakai, KL
中科院分区：
文献类型：
--
作者：
Hashimoto, Y;Sakai, KL
当说话者的声音在200毫秒的延迟后返回到自己的耳朵时，该延迟会导致说话者的讲话不那么流畅。这种现象被称为延迟听觉反馈(DAF)效应。为了通过DAF效应研究语音加工的神经机制，我们进行了一项功能磁共振成像(FMRI)实验，在该实验中，我们设计了一个范式，分别探索意识显性语音加工和自动显性语音加工，同时减少发音运动伪影。受试者被要求(1)在实时听觉反馈(Normal)下朗读视觉呈现的句子，(2)在实时听觉反馈(FAST)下快速朗读，(3)在实时听觉反馈(Slow)下缓慢朗读，(4)在DAF(延迟)下朗读。在延迟正常、延迟快和延迟慢的对比中，双侧颞上回(STG)、缘上回(SMG)和颞中回(MTG)均有显著激活。此外，我们发现在所有受试者中，STG的激活与DAF效应的程度相关。由于在正常、快速和慢速条件下的比较中，颞顶区没有表现出明显的激活，我们可以排除它的激活是由于语速或对改变的语音的注意增强的可能性。这些结果表明，颞顶区作为一种有意识的自我监控系统来支持自动语音生成系统。(C)2003年Wiley-Liss，Inc.
When a speaker's voice returns to one's own ears with a 200-ms delay, the delay causes the speaker to speak less fluently. This phenomenon is called a delayed auditory feedback (DAF) effect. To investigate neural mechanisms of speech processing through the DAF effect, we conducted a functional magnetic resonance imaging (fMRI) experiment, in which we designed a paradigm to explore the conscious overt-speech processing and the automatic overt-speech processing separately, while reducing articulatory motion artifacts. The subjects were instructed to (1) read aloud visually presented sentences under real-time auditory feedback (NORMAL), (2) read aloud rapidly under real-time auditory feedback (FAST), (3) read aloud slowly under real-time auditory feedback (SLOW), and (4) read aloud under DAF (DELAY). In the contrasts of DELAY-NORMAL, DELAY-FAST, and DELAY-SLOW, the bilateral superior temporal gyrus (STG), the supramarginal gyrus (SMG), and the middle temporal gyrus (MTG) showed significant activation. Moreover, we found that the STG activation was correlated with the degree of DAF effect for all subjects. Because the temporo-parietal regions did not show significant activation in the comparisons among NORMAL, FAST, and SLOW conditions, we can exclude the possibility that its activation is due to speech rates or enhanced attention to altered speech sounds. These results suggest that the temporo-parietal regions function as a conscious self-monitoring system to support an automatic speech production system. (C) 2003 Wiley-Liss, Inc.