EFFECT OF BREAST-FEEDING ON THE PLASMA-CHOLESTEROL AND GROWTH OF INFANTS
EFFECT OF BREAST-FEEDING ON THE PLASMA-CHOLESTEROL AND GROWTH OF INFANTS
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DOI：
10.1097/00005176-199108000-00004
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发表时间：
1991-08-01
影响因子：
2.9
通讯作者：
CHARLTON, DO
中科院分区：
文献类型：
--
作者：
JOOSTE, PL;ROSSOUW, LJ;CHARLTON, DO
在一个大型的自由生活婴儿队列（n = 512）中，从出生到1岁，纵向研究了母乳喂养对血浆胆固醇、体重和身长的影响。在该队列中，21.4%的人完全母乳喂养至少3个月，39.3%的人接受奶瓶喂养，39.3%的人接受母乳和奶瓶喂养的组合。出生时，三组的血浆胆固醇相似。3个月后，母乳喂养组的平均血浆胆固醇和高胆固醇血症的比例显著高于其他两组（P < 0.001）。这些差异在1岁时消失。母乳喂养的婴儿在3个月和12个月时体重较轻，但身长与其他组相似。这些结果表明，母乳喂养通过直接机制升高血浆胆固醇，并且这种作用仅在母乳喂养持续时持续。
The effect of breast-feeding on plasma cholesterol, body weight, and body length was studied longitudinally in a large free-living cohort of infants (n = 512) from birth until the age of 1 year. Of the cohort, 21.4% were exclusively breast-fed for at least 3 months, 39.3% received bottle-feeding, and 39.3% received a combination of breast- and bottle-feeding. At birth the plasma cholesterol was similar in the three groups. After 3 months the mean plasma cholesterol and proportion of hypercholesterolemic infants in the breast-fed group were significantly (p < 0.001) higher than that of the other two groups. These differences had disappeared at the age of 1 year. Breast-fed infants weighed less at 3 and 12 months, but body length was similar to those of the other groups. These results suggest that breast-feeding elevates plasma cholesterol by a direct mechanism and that the effect persists only as long as the breast-feeding is continued.