Microfluidic in situ mechanical testing of photopolymerized gels
Microfluidic in situ mechanical testing of photopolymerized gels
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DOI：
10.1039/c4lc01034e
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发表时间：
2015-01-01
期刊：
影响因子：
6.1
通讯作者：
Lindner, Anke
中科院分区：
文献类型：
--
作者：
Duprat, Camille;Berthet, Helene;Lindner, Anke
凝胶是微粒子制造和微生物实验的功能模板。在许多应用中，对其机械性能的控制和了解是至关重要的，但目前还没有简单的原位方法来确定这些性能。我们提出了一种新的基于微流体的方法，可以直接测量凝胶的机械性能。我们测量了凝胶束在受控流动压力下的变形，这使我们可以直接获得材料本身的杨氏模量。然后我们用这种方法测定了聚乙二醇二丙烯酸酯（PEGDA）在不同实验条件下的力学性能。凝胶的机械性能可以高度调整，产生两个数量级的杨氏模量。该方法可以很容易地实现，以允许在各种实验条件下的杨氏模量的现场直接测量和控制。
Gels are a functional template for micro-particle fabrication and microbiology experiments. The control and knowledge of their mechanical properties is critical in a number of applications, but no simple in situ method exists to determine these properties. We propose a novel microfluidic based method that directly measures the mechanical properties of the gel upon its fabrication. We measure the deformation of a gel beam under a controlled flow forcing, which gives us a direct access to the Young's modulus of the material itself. We then use this method to determine the mechanical properties of poly(ethylene glycol) diacrylate (PEGDA) under various experimental conditions. The mechanical properties of the gel can be highly tuned, yielding two order of magnitude in the Young's modulus. The method can be easily implemented to allow for an in situ direct measurement and control of Young's moduli under various experimental conditions.