OPTICAL COHERENCE TOMOGRAPHY OF CENTRAL SEROUS CHORIORETINOPATHY
OPTICAL COHERENCE TOMOGRAPHY OF CENTRAL SEROUS CHORIORETINOPATHY
复制标题
DOI：
10.1016/s0002-9394(14)73760-2
复制
发表时间：
1995-07-01
影响因子：
4.2
通讯作者：
FUJIMOTO, JG
中科院分区：
文献类型：
--
作者：
HEE, MR;PULIAFITO, CA;FUJIMOTO, JG
目的：评估一种新的成像技术的潜力，光学相干断层扫描，诊断和监测中央浆液性脉络膜视网膜病变。光学相干断层扫描是一种新型的无创、非接触成像方式，可产生高纵向分辨率的眼组织断层扫描。方法：光学相干断层扫描类似于超声波，不同之处在于它使用光而不是声音在视网膜中获得更高的图像分辨率。采用纵向分辨率为10 μ m的视网膜光学反射率横切面断层扫描，对转诊眼科中心的16例患者进行了光学相干断层扫描，初步检查显示其临床诊断为中枢浆液性脉络膜视网膜病变。光学相干断层扫描结果与裂隙灯生物显微镜、眼底摄影和荧光素血管造影相关。结果：光学相干断层扫描所产生的横切面能有效地客观量化疾病中浆液性视网膜脱离的数量。光学相干断层扫描揭示了裂隙灯生物显微镜未检测到的分离。纵向测量光学相干断层扫描成功地能够跟踪视网膜下积液的分辨率。结论：光学相干断层扫描作为一种新的、无创的诊断技术，可用于对中枢性浆液性视网膜病变进行定量检查，并客观地监测该疾病的浆液性视网膜脱离的临床病程。
PURPOSE: To assess the potential of a new imaging technique, optical coherence tomography, for the diagnosis and monitoring of central serous chorioretinopathy. Optical coherence tomography is a novel noninvasive, noncontact imaging modality that produces high longitudinal resolution, cross-sectional tomographs of ocular tissue.METHODS: Optical coherence tomography is analogous to ultrasound, except that it uses light rather than sound to obtain higher image resolution in the retina. Cross-sectional tomographs of optical reflectivity within the retina are produced with longitudinal resolution of 10 mu m, Optical coherence tomography was used to examine 16 patients at a referral eye center whose initial examination disclosed the clinical diagnosis of central serous chorioretinopathy. The optical coherence tomography results were correlated with slit-lamp biomicroscopy, fundus photography, and fluorescein angiography.RESULTS: The cross-sectional view produced by optical coherence tomography was effective in objectively quantifying the amount of serous retinal detachment in the disease. Optical coherence tomography disclosed detachments that were undetected by slit-lamp biomicroscopy. Longitudinal measurements with optical coherence tomography were successfully able to track the resolution of subretinal fluid accumulation.CONCLUSION: Optical coherence tomography is potentially useful as a new, noninvasive diagnostic technique for quantitative examination of patients with central serous chorioretinopathy and objectively monitoring the clinical course of the serous retinal detachment in this disease.