A NEW, SEMISTRUCTURED PSYCHIATRIC INTERVIEW FOR USE IN GENETIC-LINKAGE STUDIES - A REPORT ON THE RELIABILITY OF THE SSAGA
A NEW, SEMISTRUCTURED PSYCHIATRIC INTERVIEW FOR USE IN GENETIC-LINKAGE STUDIES - A REPORT ON THE RELIABILITY OF THE SSAGA
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DOI：
10.15288/jsa.1994.55.149
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发表时间：
1994-03-01
期刊：
影响因子：
--
通讯作者：
SCHUCKIT, MA
中科院分区：
文献类型：
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作者：
BUCHOLZ, KK;CADORET, R;SCHUCKIT, MA
进行了中心内和跨中心的重测研究，以研究一种新的、半结构化、综合性、多种诊断的精神病学访谈的可靠性，该访谈被用于一项酗酒的多地点基因连锁研究。两项研究的结果都表明，酒精中毒遗传学半结构化评估（SSAGA）对《精神障碍诊断与统计手册》第三版修订本（DSM - III - R）中的物质依赖障碍可靠性较高，但对物质滥用障碍的可靠性则较低。在两项研究中，抑郁症的可靠性都较好，但反社会人格障碍（ASP）的情况则不一。研究结果是根据特定的物质依赖和滥用诊断以及抑郁症和ASP呈现的。通过所使用物质的类型来检验特定标准的可靠性。尽管SSAGA旨在为酗酒提供广泛的表型分析，但对其新特性的回顾表明，它适用于各种家庭研究，而不仅仅是那些侧重于物质滥用的研究。
Within- and cross-center test-retest studies were conducted to study the reliability of a new, semistructured, comprehensive, polydiagnostic psychiatric interview being used in a multisite genetic linkage study of alcoholism. Findings from both studies indicated that reliability for the Semi-Structured Assessment for the Genetics of Alcoholism (SSAGA) was high for DSM-III-R substance dependence disorders, but less so for substance abuse disorders. Reliability of depression was good in both studies, but mixed for anti-social personality disorder (ASP). Findings are presented in terms of specific substance dependence and abuse diagnoses, as well as for depression and ASP. Criterion-specific reliabilities are examined by type of substance used. Although SSAGA was designed to provide for broad phenotyping of alcoholism, review of its new features suggests its suitability for a variety of family studies, not just those focusing on substance abuse.