Cell cycle dependence for the induction of 6-thioguanine-resistant mutations: G2/M stage is distinctively sensitive to 252Cf neutrons but not to 60Co gamma-rays.
Cell cycle dependence for the induction of 6-thioguanine-resistant mutations: G2/M stage is distinctively sensitive to 252Cf neutrons but not to 60Co gamma-rays.
复制标题
诱导 6-硫鸟嘌呤抗性突变的细胞周期依赖性:G2/M 阶段对 252Cf 中子特别敏感,但对 60Co 伽马射线不敏感。
DOI:
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发表时间:
1993
影响因子:
2.6
通讯作者:
S. Sawada
中科院分区:
文献类型:
--
作者:
H. Tauchi;N. Nakamura;S. Sawada
Cell cycle dependence for the induction of 6-thioguanine-resistant mutation was investigated using synchronized mouse L5178Y cells after exposure to 4 Gy to 60Co gamma-rays or 1 Gy of 252Cf radiation (fission neutrons). Maximal mutation frequency was observed immediately after release from colcemid block (G2/M phase) after 252Cf radiation, whereas it was 1 h after the release (G1 phase) after 60Co gamma-rays. When the mutation frequency was plotted against the surviving fraction, a general correlation was observed between the two parameters except for G2/M and G1 phases which were more mutable per lethal event for 252Cf and 60Co radiations, respectively.
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DOI:
10.1080/09553008414551011
发表时间:
1984
期刊:
International journal of radiation biology and related studies in physics, chemistry, and medicine
影响因子:
--
作者:
Hill,CK;Han,A;Elkind,MM
通讯作者:
Elkind,MM
影响因子:
3.4
作者:
Kronenberg,A
通讯作者:
Kronenberg,A
影响因子:
2.6
作者:
Cao,J;Wells,RL;Elkind,MM
通讯作者:
Elkind,MM
影响因子:
3.4
作者:
Miller,RC;Geard,CR;Geard,MJ;Hall,EJ
通讯作者:
Hall,EJ