The Genetic and Phenotypic Basis of Infertility in Men With Pediatric Urologic Disorders
The Genetic and Phenotypic Basis of Infertility in Men With Pediatric Urologic Disorders
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DOI：
10.1016/j.urology.2010.03.011
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发表时间：
2010-07-01
期刊：
影响因子：
2.1
通讯作者：
Turek, Paul J.
中科院分区：
文献类型：
--
作者：
Hsieh, Michael H.;Hollander, Adam;Turek, Paul J.
男性因素是许多夫妇不孕不育的主要因素。男性伴侣中存在先天性泌尿生殖系统异常可导致男性不育。我们回顾了由儿童泌尿系统疾病引起的男性不育症的最新治疗方法和结果。根据疾病是否通过睾丸前、睾丸或睾丸后效应导致不育症进行分类。尽管儿科泌尿系统疾病的复杂性会影响生育能力，但通过辅助生殖技术进行自然亲子鉴定和亲子鉴定是很常见的。鉴于最近不孕不育治疗的重大进展，亲子关系很可能在未来导致许多目前无法治愈的儿科疾病。泌尿外科76：25-31,2010。(C)2010年爱思唯尔公司。
Male factor is a major component of infertility for many couples. The presence of congenital genitourinary anomalies in male partners can cause male infertility. We reviewed the state-of-the-art treatment and outcomes for male infertility caused by pediatric urologic disorders. Disorders were classified by whether they led to infertility through pre-testis, testicular, or post-testis effects. Despite the complexity of pediatric urologic disorders that can affect fertility, natural paternity and paternity through assisted reproductive technology are common. Given the significant recent advances in infertility treatments, paternity with many currently untreatable pediatric disorders is likely in the future. UROLOGY 76: 25-31, 2010. (C) 2010 Elsevier Inc.