Cytotoxic α/β+ and γ/δ+ T cells in murine intestinal epithelium
Cytotoxic α/β+ and γ/δ+ T cells in murine intestinal epithelium
复制标题
小鼠肠上皮中的细胞毒性 α/β+ 和 γ/δ+ T 细胞
DOI:
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发表时间:
1990
期刊:
影响因子:
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通讯作者:
T. Macdonald
中科院分区:
文献类型:
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作者:
J. Viney;P. Kilshaw;T. Macdonald
Murine intraepithelial lymphocytes (IEL) consist of two main populations. Approximately half are Thy‐1+, most of which are CD3+, T cell receptor (TcR) α/β+, and the remainder are Thy‐1−, most of which are CD3+, TcR α/β (presumably TcR γ/δ+). In redirected cytotoxicity assays, TcR α/β+ IEL are potent cytotoxic effectors. Thy‐1−, CD3+, TcR α/β− IEL isolated from athymic mice are also cytotoxic. Thus, regardless of TcR usage or Thy‐1 expression, IEL are cytotoxic effectors.
DOI:
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发表时间:
1989
期刊:
Journal of immunology (Baltimore, Md. : 1950)
影响因子:
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作者:
Kubo,RT;Born,W;Kappler,JW;Marrack,P;Pigeon,M
通讯作者:
Pigeon,M