Intracardiac infusion of acetylcholine in primary pulmonary hypertension.
Intracardiac infusion of acetylcholine in primary pulmonary hypertension.
复制标题
心内输注乙酰胆碱治疗原发性肺动脉高压。
DOI：
10.1016/0002-8703(60)90202-7
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发表时间：
1960
影响因子：
4.8
通讯作者：
J. Widrich
中科院分区：
文献类型：
--
作者：
P. Samet;W. Bernstein;J. Widrich
本文报告两例原发性肺动脉高压，并给出右心导管检查结果。输注乙酰胆碱导致一名受试者在休息和运动时肺动脉压大幅下降。在第二例受试者中，输注乙酰胆碱导致肺动脉压降低程度较小，但仍显着。必须满足的标准，然后才得出结论，在肺血管床血管舒张或血管收缩的存在进行了讨论。
Two cases of primary pulmonary hypertension are presented, and the results of right heart catheterization are given. Infusion of acetylcholine caused large decreases in pulmonary arterial pressure in one subject, both at rest and during exercise. In the second subject, infusion of acetylcholine resulted in a lesser but still significant decrease in pulmonary arterial pressure. The criteria that must be met before conclusions are drawn as to the existence of vasodilation or vasoconstriction in the pulmonary vascular bed are discussed.