Effect of baricity on spinal anaesthesia with bupivacaine.
Effect of baricity on spinal anaesthesia with bupivacaine.
复制标题
气压对布比卡因脊髓麻醉的影响。
DOI：
10.1093/bja/53.3.279
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发表时间：
1981
影响因子：
9.8
通讯作者：
D. Scott
中科院分区：
文献类型：
--
作者：
W. Chambers;H. Edstrom;D. Scott
在一项双盲研究中，使用0.5%布比卡因3 ml（无葡萄糖）、5%葡萄糖或8%葡萄糖进行脊髓麻醉，所有三种溶液均提供了持续良好的神经阻滞。高压溶液（5%和8%葡萄糖）产生更大的头向扩散，适合下腹部手术，而普通溶液（无葡萄糖）很少影响胸神经。心血管变化更显着的高压溶液，但只有两次需要治疗。封闭时间不受气压的影响，在140-160 min之间。
In a double-blind study of spinal anaesthesia with 0.5% bupivacaine 3 ml with no glucose, 5% glucose or 8% glucose all three solutions gave consistently good nerve blocks. The hyperbaric solutions (5% and 8% glucose) produced a greater cephalad spread and were suitable for lower abdominal surgery, whereas the plain solution (no glucose) seldom affected the thoracic nerves. Cardiovascular changes were more marked with the hyperbaric solutions but only necessitated treatment on two occasions. The duration of block was not affected by baricity and was in the range 140-160 min.