Device artifact reduction for magnetic resonance imaging of patients with implantable cardioverter-defibrillators and ventricular tachycardia: late gadolinium enhancement correlation with electroanatomic mapping.

Device artifact reduction for magnetic resonance imaging of patients with implantable cardioverter-defibrillators and ventricular tachycardia: late gadolinium enhancement correlation with electroanatomic mapping.
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DOI:
10.1016/j.hrthm.2013.10.032
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发表时间:
2014-02
期刊:
影响因子:
5.5
通讯作者:
Hu, Peng
Hu, Peng
中科院分区:
医学2区
文献类型:
--
作者:
Stevens, Steven M.;Tung, Roderick;Rashid, Shams;Gima, Jean;Cote, Shelly;Pavez, Geraldine;Khan, Sarah;Ennis, Daniel B.;Finn, J. Paul;Boyle, Noel;Shivkumar, Kalyanam;Hu, Peng

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心室瘢痕的晚期钆增强(LGE)MRI已被证明可准确检测和表征心律失常基质。然而,大多数接受室性心动过速(VT)消融的患者都有植入式心律转复除颤器(ICD),这会模糊MRI的图像完整性和临床实用性。开发并确认用于器械伪影去除的宽带LGE MRI技术。开发了一种新的宽带LGE MRI技术,以改善ICD患者的瘢痕评价。在18例植入ICD的患者中测试了宽带技术和标准LGE MRI。18例患者中有13例采用心内膜和/或心外膜入路进行了室性心动过速消融,并分析了MRI上识别的瘢痕与电解剖标测之间的相关性。使用标准MRI的16/18例患者存在高强度伪影,使用宽带LGE消除了高强度伪影,并允许15/16例患者进行MRI解释。所有患者的ICD电极导线特征在MRI后均确认为无变化,且无不良事件。11/18例患者可见LGE瘢痕。在15名使用宽带LGE可显示心肌的患者中,10名患者在使用标准LGE时出现LGE瘢痕,5名患者在图像伪影区域出现正常心肌。使用宽带MRI和EAM测量的左心室瘢痕大小与R2=0.83,P=0.00003相关。宽带LGE-MRI提高了心肌可视化的能力,用于临床解释,这与VT消融期间的EAM结果相关性良好。
Late Gadolinium Enhancement (LGE) MRI of ventricular scar has been shown to be accurate for detection and characterization of arrhythmia substrates. However, the majority of patients referred for ventricular tachycardia (VT) ablation have an implantable cardioverter defibrillator (ICD), which obscures image integrity and the clinical utility of MRI. To develop and validate a wideband LGE MRI technique for device artifact removal. A novel wideband LGE MRI technique was developed to allow for improved scar evaluation on patients with ICDs. The wideband technique and the standard LGE MRI were tested on 18 patients with ICDs. VT ablation was performed in 13 of 18 patients with either endocardial and/or epicardial approach and the correlation between the scar identified on MRI and electroanatomical mapping was analyzed. Hyper-intensity artifact was present in 16/18 of patients using standard MRI, which was eliminated using the wideband LGE and allowed for MRI interpretation in 15/16 patients. All patients had ICD lead characteristics confirmed as unchanged post- MRI and had no adverse events. LGE scar was seen in 11/18 patients. Among the 15 patients where wideband LGE allowed visualization of myocardium, 10 had LGE scar and 5 had normal myocardium in the regions with image artifacts when using the standard LGE. The left ventricular scar size measurements using wideband MRI and EAM were correlated with R2=0.83, P=0.00003. The wideband LGE-MRI improves the ability to visualize myocardium for clinical interpretation, which correlated well with EAM findings during VT ablation.
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