The functional neuroanatomy of simple calculation and number repetition: A parametric PET activation study

The functional neuroanatomy of simple calculation and number repetition: A parametric PET activation study
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DOI:
10.1006/nimg.2000.0640
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发表时间:
2000-11-01
期刊:
影响因子:
5.7
通讯作者:
Watson, JDG
Watson, JDG
中科院分区:
医学1区
文献类型:
--
作者:
Cowell, SF;Egan, GF;Watson, JDG

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我们用正电子发射断层扫描(PET)检查了12名右利手正常志愿者在完成简单计算任务或仅仅重复数字时的大脑激活模式。使用参数实验设计,在计算过程中,我们发现内侧额叶/扣带回、左背外侧前额叶皮层、左前岛叶皮层和右前岛叶皮层/壳核、左外侧顶叶皮层和内侧丘脑激活,双侧下感觉运动皮层、双侧颞区和左下额叶皮层参与数字重复,这些结果表明,一个功能解剖网络简单的计算,其中包括方面的注意,听觉和运动处理和语音存储和发音回路组件的工作记忆,他们增加了一些支持顶叶皮层在计算任务中的特殊作用。(C)北京大学出版社.
We examined cerebral activation patterns with positron emission tomography (PET) in 12 right-handed normal volunteers while they were completing simple calculation tasks or merely repeating numbers. Using a parametric experimental design, during calculation we found activation in the medial frontal/cingulate gyri, left dorsolateral prefrontal cortex, left anterior insular cortex and right anterior insular cortex/putamen, left lateral parietal cortex, and the medial thalamus, Number repetition engaged bilateral inferior sensorimotor cortex, bilateral temporal areas, and left inferior frontal cortex, These results suggest a functional anatomical network for simple calculation, which includes aspects of attention, auditory, and motor processing and the phonological store and articulatory loop components of working memory; they add some support for a special role of the parietal cortex in calculation tasks. (C) 2000 Academic Press.