Interpreting the continued decline in the average age at menarche: Results from two nationally representative surveys of US girls studied 10 years apart
Interpreting the continued decline in the average age at menarche: Results from two nationally representative surveys of US girls studied 10 years apart
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DOI：
10.1016/j.jpeds.2005.07.016
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发表时间：
2005-12-01
影响因子：
5.1
通讯作者：
Must, A
中科院分区：
文献类型：
--
作者：
Anderson, SE;Must, A
目的：确定在过去十年中，美国的平均初潮年龄是否下降，以及初潮时间、体重状况和种族/民族之间的关系是否发生变化。研究设计：将1988-1994年国家健康与营养调查（NHANES）III（1988-1994）中女孩（n = 1577）的相对体重、种族/民族和月经初潮状况与1999-2002年NHANES中女孩（n = 1720）的相对体重、种族/民族和月经初潮状况进行比较。概率分析估计了总体初潮时的平均年龄，也按人种/种族进行了估计。Logistic回归评估了相对体重和种族/民族与月经初潮状态的相关性。结果在美国，平均初潮年龄从1988-1994年的12.53岁（95%CI = 12.43 ~ 12.63岁）下降到1999-2002年的12.34岁（95%CI = 12.24 ~ 12.45岁）。按种族/民族划分，月经初潮的平均年龄估计如下：非西班牙裔白人，12.57岁（95% CI = 12.45 - 12.69岁）和12.52岁（95% CI = 12.38 - 12.67岁）;非西班牙裔黑人，12.09岁（95% CI = 11.82 - 12.36年）和12.06年（95% CI = 11.81至12.32岁）;墨西哥裔美国人，12.24岁（95% CI = 11.88至12.59岁）和12.09岁（95% CI 11.81至12.37岁）。较高的相对体重与达到初潮的可能性增加始终相关。1988-1994年和1999-2002年之间，美国的平均初潮年龄下降了2.3个月;按种族/民族划分，下降幅度要小得多。在解释初潮年龄趋势时，应考虑人种/种族和相对体重的人群分布变化。
Objectives To determine whether average age at menarche declined in the United States during the past decade, and whether associations between menarcheal timing, weight status, and race/ethnicity changed. Study design Relative weight, race/ethnicity, and menarcheal status of girls (n = 1577) in the National Health and Nutrition Examination Survey (NHANES) III (1988-1994) were compared with those of girls (n = 1720) in NHANES 1999-2002. Probit analysis estimated average age at menarche overall and also by race/ethnicity. Logistic regression assessed associations of relative weight and race/ethnicity with menarcheal status. Results In the United States, average age at menarche declined from 12.53 years (95% confidence interval [CI] = 12.43 to 12.63 years) in 1988-1994 to 12.34 years (95% CI = 12.24 to 12.45 years) in 1999-2002. By race/ethnicity, average age at menarche estimates were as follows: non-Hispanic whites, 12.57 years (95% CI = 12.45 to 12.69 years) and 12.52 years (95% CI = 12.38 to 12.67 years); non-Hispanic blacks, 12.09 years (95% CI = 11.82 to 12.36 years) and 12.06 years (95% CI = 11.81 to 12.32 years); and Mexican Americans, 12.24 years (95% CI = 11.88 to 12.59 years) and 12.09 years (95% CI 11.81 to 12.37 years). Higher relative weight was consistently associated with increased likelihood of having reached menarche. Conclusions Average age at menarche in the United States declined by 2.3 months between 1988-1994 and 1999-2002; by race/ethnicity, declines were considerably smaller. Changes in the population distribution of race/ethnicity and relative weight should be considered when interpreting trends in age at menarche.