Visual scanning deficits in schizophrenia and their relationship to executive functioning impairment
Visual scanning deficits in schizophrenia and their relationship to executive functioning impairment
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DOI：
10.1016/j.schres.2004.07.008
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发表时间：
2005-04-01
影响因子：
4.5
通讯作者：
Perry, W
中科院分区：
文献类型：
--
作者：
Minassian, A;Granholm, E;Perry, W
在精神分裂症患者中观察到对面部、物体和线条画的异常视觉扫描，并认为这反映了神经认知障碍。在这项研究中，同时测量方法被用来评估精神分裂症患者是否表现出限制性的视觉扫描时，面对一个复杂的解决问题的刺激，以及视觉扫描缺陷是否是僵化的思维的预测。38名精神分裂症患者和30名对照参与者进行了罗夏墨迹测试，同时监测眼球运动，记录对刺激的言语反应，并使用罗夏重复和持续量表对不灵活的思维进行评分。精神分裂症患者表现出更少和更长的视觉固定和更短的总扫描路径相对于比较参与者，但没有不同的平均扫描路径长度。在患者中，较少的注视与较高的言语持续频率相关。扫描措施和症状之间的相关性表明，阴性症状与最小扫描或“盯着”的方法。结果支持以前的研究结果限制视觉扫描精神分裂症患者，与以前观察到的视觉扫描和症状之间的关系是一致的，并建议在复杂的问题解决任务的视觉组织缺陷可能与认知能力和额叶执行功能障碍。(C)2004 Elsevier B.V.保留所有权利。
Abnormal visual scanning of faces, objects, and line drawings has been observed in patients with schizophrenia and is thought to reflect neurocognitive impairment. In this study, a simultaneous measurement approach was used to assess whether schizophrenia patients demonstrate restricted visual scanning when confronted with a complex problem-solving stimulus, and whether visual scanning deficits are predictive of inflexible thinking. Thirty-eight schizophrenia patients and 30 comparison participants were presented with Rorschach inkblots while eye movements were monitored and verbal responses to the stimuli were recorded and scored for inflexible thinking using the Rorschach Repetition and Perseveration Scale. Schizophrenia patients demonstrated fewer and longer visual fixations and shorter total scanpath relative to comparison participants but did not differ on mean scanpath length. Among patients, fewer fixations were associated with a higher frequency of verbal perseverations. Correlations between scanning measures and symptoms showed that negative symptoms were related to a minimal scanning or "staring" approach. Results support previous findings of restricted visual scanning in schizophrenia patients, are consistent with previously observed relationships between visual scanning and symptom profiles, and suggest that visual organizational deficits during complex problem-solving tasks may be related to cognitive inflexibility and frontal-executive dysfunction. (C) 2004 Elsevier B.V. All rights reserved.