[The Swiss Organ Living Donor Health Registry (SOL-DHR)].
[The Swiss Organ Living Donor Health Registry (SOL-DHR)].
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[瑞士器官活体捐赠者健康登记处 (SOL-DHR)]。
DOI：
10.1024/0040-5930.62.7.449
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发表时间：
2005
期刊：
影响因子：
--
通讯作者：
D. Tsinalis
中科院分区：
文献类型：
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作者：
G. Thiel;C. Nolte;D. Tsinalis
瑞士活体器官捐献者健康登记处（SOL-DHR）于1993年4月开始运作。其目的是前瞻性和连续的后续捐助者的长期健康。在1993年至2005年1月期间，登记和跟踪了737例活肾捐赠。三分之二的捐赠者是女性，三分之二的接受者是男性。最常见的三种关系是生活伴侣、父母和兄弟姐妹（各占约30%）。10%的捐赠者由于居住在国外而无法跟踪，5%的捐赠者由于搬家后失去了当前地址。9例供体死亡（4例恶性肿瘤，2例交通事故，1例心肌梗死，1例中风和1例自杀），非由于肾脏捐献。围手术期并发症与年龄有关，40岁以下供体为17%，70岁以上供体为46%。远期并发症可分为外科并发症、内科并发症和心理并发症。最常见的手术长期并发症是疼痛（瘢痕、背部、腹部）和疝。主要的内科并发症是高血压（捐赠后7年为35%）和蛋白尿率上升（7年为9%）。尽管高血压并不高于年龄匹配的瑞士对照人群，但未经治疗的高血压被认为比双肾患者发生肾小球硬化的风险更高。无供体发生终末期肾衰竭。使用SF-8-测试量化心理健康，平均MCS（心理成分总结）为54.3 +/- 7.8，而年龄匹配的对照人群为52.9 +/- 7.7。6.2%的供体MCS较低（< 40），2.2%的供体MCS非常低（< 25）。94.4%的捐赠者会再次捐赠，而4.3%的人不会（大多数是女性）。不再次捐献的原因主要与肾脏接受者的预后不佳，或长期的重大疼痛或对器官捐献前后的医疗处理（信息不足，错误的建议）感到失望有关。只有肾脏或肝脏捐献者才能成为会员的瑞士活体器官捐献者协会正在组织针对疼痛、心理和经济问题的自助小组（有健康保险）。对SOL-DHR的组织和财政支助作了简要说明。大多数活体肾脏捐献者对SOL-DHR提供的免费护理非常满意。
The Swiss Organ Living Donor Health Registry (SOL-DHR) started in April 1993. The purpose was the prospective and sequential follow up of donors long-term health. Between 1993 and January 2005 737 Living Kidney donations were registered and followed. Two thirds of donors were female and two thirds of recipients male. The three most common relations were life-partners, parents and siblings (approximately 30% each). 10% of donors could not be followed since living far abroad and 5% were lost due to missing current address after moving. 9 donors died (4 malignancies, 2 traffic accidents, 1 myocardial infarction, 1 stroke and 1 suicide), non due to kidney donation. Perioperative complications were age dependent, ranging from 17% in donors below the age of 40 year and 46% in donors older than 70 years. The longterm complications were divided in surgical, medical and psychological ones. The most common surgical long-term complications were pain (cicatrice, back, abdomen) and hernias. The major medical complications were hypertension (35% at seven years after donation) and rising rate of Albuminuria (9% at seven years). Although hypertension was not higher than in an age matched Swiss control population, untreated hypertension was regarded as the higher risk for development of glomerulosclerosis than in people with two kidneys. No donor went into end stage renal failure. Using the SF-8-Test to quantify the psychological well-being the mean MCS (mental component summary) was 54.3 +/- 7.8 as compared to 52.9 +/- 7.7 in the age matched control population. MCS was low (< 40) in 6.2% and very low (< 25) in 2.2% of donors. 94.4 % of donors would donate again, while 4.3% would not (mostly women). The reasons not to donate again was mainly related to poor outcome of the kidney recipient, or long-lasting major pain or disappointment about medical handling before (not enough information, wrong advice) and after organ donation. The association of Swiss Living Organ Donors, where only kidney or liver donors can become a member, are organising self-help-groups for pain, psychological and financial problems (with health insurances). The organisation and financial support of SOL-DHR is briefly described. The waste majority of living kidney donors are very satisfied about the free care given by SOL-DHR.