Clinical Practice Guidelines for Clostridium difficile Infection in Adults and Children: 2017 Update by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA)
Clinical Practice Guidelines for Clostridium difficile Infection in Adults and Children: 2017 Update by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA)
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DOI：
10.1093/cid/cix1085
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发表时间：
2018-04-01
影响因子：
11.8
通讯作者：
Wilcox, Mark H.
中科院分区：
文献类型：
--
作者：
McDonald, L. Clifford;Gerding, Dale N.;Wilcox, Mark H.
美国传染病学会（IDSA）和美国医疗保健流行病学学会（SHEA）召集了一个专家小组，以更新2010年成人艰难梭菌感染（CDI）的临床实践指南。该更新纳入了对儿童的建议（遵循成人对流行病学，诊断和治疗的建议），包括对这种感染管理的重大变化，并反映了对最佳诊断方法的不断演变的争议。艰难梭菌仍然是医疗保健相关腹泻的最重要原因，并已成为美国成人医疗保健相关感染的最常见原因。此外，C.艰难梭菌已经确立了其自身作为重要的社区病原体的地位。尽管流行性和强毒核糖体型027菌株的流行率随着欧洲部分地区的总体CDI率而沿着显著下降，但它仍然是美国最常见的菌株之一，在美国，它引起相当多的少数CDI，特别是医疗保健相关的CDI。本指南更新了关于流行病学、诊断、治疗、感染预防和环境管理的建议。
A panel of experts was convened by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA) to update the 2010 clinical practice guideline on Clostridium difficile infection (CDI) in adults. The update, which has incorporated recommendations for children (following the adult recommendations for epidemiology, diagnosis, and treatment), includes significant changes in the management of this infection and reflects the evolving controversy over best methods for diagnosis. Clostridium difficile remains the most important cause of healthcare-associated diarrhea and has become the most commonly identified cause of healthcare-associated infection in adults in the United States. Moreover, C. difficile has established itself as an important community pathogen. Although the prevalence of the epidemic and virulent ribotype 027 strain has declined markedly along with overall CDI rates in parts of Europe, it remains one of the most commonly identified strains in the United States where it causes a sizable minority of CDIs, especially healthcare-associated CDIs. This guideline updates recommendations regarding epidemiology, diagnosis, treatment, infection prevention, and environmental management.