SURVIVAL OF TRICHURIS-MURIS IN WILD POPULATIONS OF ITS NATURAL HOSTS
SURVIVAL OF TRICHURIS-MURIS IN WILD POPULATIONS OF ITS NATURAL HOSTS
复制标题
DOI：
10.1017/s0031182000046382
复制
发表时间：
1973-01-01
期刊：
影响因子：
2.4
通讯作者：
WAKELIN, D
中科院分区：
文献类型：
--
作者：
BEHNKE, JM;WAKELIN, D
野生田鼠（Apodemus sylvaticus）和实验室饲养的野生家鼠（Mus musculus）实验感染鼠毛线虫的结果表明，该寄生虫引起的免疫反应与先前在实验室小鼠品系中描述的相似。在实验室老鼠身上进行的实验表明，这种寄生虫只有在小的单次感染或多次低水平感染时才能性成熟。一项对43只自然感染鼠弓形虫的野生家鼠的调查表明，除了6只携带较大成年虫负担的雌性小鼠外，大多数小鼠的小虫负担模式与重复低水平感染的情况一致。这表明，在这些小鼠中，怀孕和/或哺乳可能抑制了免疫反应，使蠕虫负担的积累超过了蠕虫排出的阈值。
The results of experimental infections of Trichuris muris in wild field mice (Apodemus sylvaticus) and laboratory-bred wild house mice (Mus musculus) showed that the parasite elicited an immune response similar to that previously described in strains of laboratory mice. Experiments in laboratory mice showed that the parasite was able to become sexually mature only when small single infections or repeated low-level infections were given. A survey of a population of 43 wild house mice naturally infected with T. muris showed that the pattern of small worm burdens in the majority of mice was consistent with a situation of repeated low-level infection, except in the case of six female mice which harboured larger mature worm burdens. It is suggested that in these mice pregnancy and/or lactation may have suppressed the immune response, allowing the accumulation of a worm burden in excess of the threshold for worm expulsion.