Opium-related sphincter of Oddi dysfunction causing double duct sign.
Opium-related sphincter of Oddi dysfunction causing double duct sign.
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DOI：
10.4103/2303-9027.187892
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发表时间：
2016-07
影响因子：
4.5
通讯作者：
Bhasin DK
中科院分区：
文献类型：
--
作者：
Sharma V;Rana SS;Chaudhary V;Dhaka N;Manrai M;Sivalingam J;Sharma R;Dutta U;Bhasin DK
胆总管和胰管同时扩张的双管征通常与恶性疾病如胰头或壶腹恶性肿瘤有关。偶尔，良性原因如慢性胰腺炎或Oddi括约肌功能障碍（SOD）也可引起双管征。慢性鸦片滥用是一种罕见的原因，双管征，内镜超声（EUS）的结果，这种罕见的实体偶尔有报道。我们报告一位54岁的男性，有长期酒精和阿片类药物滥用史，因腹痛发作进行评估，发现有阿片类药物相关的SOD，并通过胆道括约肌切开术得到改善。进行EUS以排除恶性肿瘤，并显示末端CBD周围的低回声突出，提示肌肉肥大。
Double duct sign where there is a simultaneous dilatation of both the common bile duct (CBD) and pancreatic duct is usually associated with sinister causes like malignancies of pancreatic head or ampulla. Occasionally, benign causes like chronic pancreatitis or sphincter of Oddi dysfunction (SOD) may cause double duct sign. Chronic opium abuse is a rare cause of the double duct sign, and endoscopic ultrasound (EUS) findings of this rare entity have been occasionally reported. We report about a 54-year-old male with a history of chronic alcohol and opioid abuse evaluated for episodes of abdominal pain and found to have opioid-related SOD and improved with biliary sphincterotomy. EUS was done to rule out malignancy and revealed hypoechoic prominence around terminal CBD suggestive of hypertrophied muscle.