Distraction produces an increase in pain-evoked anterior cingulate activity
Distraction produces an increase in pain-evoked anterior cingulate activity
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DOI：
10.1111/j.1469-8986.2004.00186.x
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发表时间：
2004-07-01
期刊：
影响因子：
3.7
通讯作者：
Dowman, R
中科院分区：
文献类型：
--
作者：
Dowman, R
本研究探讨了注意力分散对前扣带回（ACC）疼痛诱发活动的影响。28名健康成年人在参加条件下给予腓肠神经痛苦的电刺激，在那里他们对每个电刺激的主观幅度进行评级，并在分心条件下，他们执行算术分心任务。疼痛诱发的ACC活动的幅度估计从偶极子源定位分析的体感诱发电位。主观疼痛评分较小，疼痛诱发的ACC活动在分心条件下比在出席条件下更大。最近的局部脑血流研究也报道了与注意力分散相关的疼痛诱发的ACC活动的增加。我们的研究结果证实了这些报道，并验证了分心效应特别涉及疼痛诱发的ACC活动。注意力分散任务的认知需求提出了这样的可能性，即疼痛诱发的ACC活动可能至少部分地参与反应竞争和/或将注意力定向到疼痛刺激。
This study examined the effects of distraction on pain-evoked activity in the anterior cingulate cortex (ACC). Twenty-eight healthy adults were given painful electrical stimulation of the sural nerve during an attend condition, where they rated the subjective magnitude of each electrical stimulus, and during a distraction condition, where they performed an arithmetic distraction task. The magnitude of the pain-evoked ACC activity was estimated from the dipole source localization analysis of the somatosensory evoked potential. Subjective pain ratings were smaller and pain-evoked ACC activity was larger during the distraction condition than during the attend condition. Recent regional cerebral blood flow studies have also reported a distraction-related increase in pain-evoked ACC activity. Our results confirm these reports, and verify that the distraction effect specifically involves pain-evoked ACC activity. The cognitive demands of the distraction task present the possibility that the pain-evoked ACC activity might be involved, at least in part, in response competition and/or orienting attention toward painful stimuli.