Three-dimensional geometric comparison of partial and complete flexible mitral annuloplasty rings

Three-dimensional geometric comparison of partial and complete flexible mitral annuloplasty rings
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DOI:
10.1067/mtc.2001.116313
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发表时间:
2001-10-01
影响因子:
6
通讯作者:
Miller, DC
Miller, DC
中科院分区:
医学1区
文献类型:
--
作者:
Dagum, P;Timek, T;Miller, DC

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背景资料:以前已经在绵羊中显示,二尖瓣环在心动周期期间的生理动力学被完全环成形术废除,但最近的临床研究表明,柔性部分环成形术保留了正常的二尖瓣环动力学。采用弹性Tailor部分瓣环成形术的动物(n = 6; St Jude Medical,Inc,St Paul,Minn);以及采用弹性Duran瓣环成形术的动物(n = 7; Medtronic,Inc,Minneapolis,Minn)。恢复7 ~ 110天后,通过双平面电影透视测量三维标记坐标。二尖瓣环面积和折叠(定义为二尖瓣环从最小二乘平面的位移)和二尖瓣环隔-外侧和连合-连合尺寸在整个心动周期中每17 ms从三维标记坐标计算。在无成形环对照组中,二尖瓣环面积范围为8.0 +/- 0.2至7.2 +/- 0.2 cm(2)(10% +/- 2%),间隔-外侧和连合-连合的尺寸从27.7 +/- 0.4到25.9 +/- 0.4 mm不等(7% +/- 1%)和38.2 +/- 0.8至36.4 +/- 0.8 mm(5% +/- 1%)(平均值的平均标准误,P
Background: It has previously been shown in sheep that mitral annular physiologic dynamics during the cardiac cycle are abolished by complete ring annuloplasty, but recent clinical studies suggest that flexible partial ring annuloplasty preserves normal mitral annular dynamics.Methods: Eight radiopaque markers were sutured equidistantly around the mitral anulus in 3 groups of sheep: no-ring control animals (n = 16); animals with a flexible Tailor partial ring annuloplasty (n = 6; St Jude Medical, Inc, St Paul, Minn); and animals with a flexible Duran ring annuloplasty (n = 7; Medtronic, Inc, Minneapolis, Minn). After 7 to 110 days' recovery, 3-dimensional marker coordinates were measured by biplane cinefluoroscopy. Mitral annular area and folding (defined as displacement of the mitral anulus from a least-squares plane) and mitral annular septal-lateral and commissure-commissure dimensions were calculated from the 3-dimensional marker coordinates throughout the cardiac cycle every 17 ms.Results: In the no-ring control group mitral annular area varied from 8.0 +/- 0.2 to 7.2 +/- 0.2 cm(2) (10% +/- 2%), and the septal-lateral and commissure-commissure dimensions varied from 27.7 +/- 0.4 to 25.9 +/- 0.4 mm (7% +/- 1%) and from 38.2 +/- 0.8 to 36.4 +/- 0.8 mm (5% +/- 1%), respectively (mean standard error of the mean, P