Intradialytic hypotension, blood pressure changes and mortality risk in incident hemodialysis patients

Intradialytic hypotension, blood pressure changes and mortality risk in incident hemodialysis patients
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DOI:
10.1093/ndt/gfx037
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发表时间:
2018-01-01
影响因子:
6.1
通讯作者:
Kalantar-Zadeh, Kamyar
Kalantar-Zadeh, Kamyar
中科院分区:
医学1区
文献类型:
--
作者:
Chou, Jason A.;Streja, Elani;Kalantar-Zadeh, Kamyar

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背景。透析中低血压(IDH)经常发生在维持性血液透析(HD)患者中,并且可能与较高的死亡率相关。我们假设透析内收缩压最低点 (niSBP) 与死亡风险呈负相关,而 iSBP 变化 (Delta) 和 IDH 频率与全因死亡率逐渐相关。方法。在美国 5 年期间(2007-11 年)112 013 名 HD 患者的队列中,使用 niSBP、Delta iSBP(HD 前 SBP 减去 niSBP)和 IDH 频率(使用 niSBP 进行 HD 治疗的比例)
Background. Intradialytic hypotension (IDH) occurs frequently inmaintenance hemodialysis (HD) patients and may be associated with higher mortality. We hypothesize that nadir intradialytic systolic blood pressure (niSBP) is inversely related to death risk while iSBP change (Delta) and IDH frequency are incrementally associated with all-cause mortality.Methods. In a US-based cohort of 112 013 incident HD patients over a 5-year period (2007-11), using niSBP, Delta iSBP (pre-HD SBP minus niSBP) and IDH frequency (proportion of HD treatments with niSBP