Clinico-pathologic correlates of BRAF mutation status in 207 consecutive patients with metastatic melanoma.

Clinico-pathologic correlates of BRAF mutation status in 207 consecutive patients with metastatic melanoma.
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207 名连续转移性黑色素瘤患者 BRAF 突变状态的临床病理相关性。

DOI:
10.1200/jco.2010.28.15_suppl.8548
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发表时间:
2010
期刊:
影响因子:
--
通讯作者:
R. Kefford
R. Kefford
中科院分区:
--
文献类型:
--
作者:
G. Long;A. Menzies;A. Nagrial;L. Haydu;A. Hamilton;G. Mann;T. M. Hughes;J. Thompson;R. Scolyer;R. Kefford

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8548背景:选择性靶向致癌突变体(mut)BRAF的药物显示出对携带这些突变的转移性黑素瘤(MM)的活性。鉴别mut B的临床病理特征
8548 Background: Drugs selectively targeting oncogenic mutant (mut) BRAF show activity against metastatic melanoma (MM) carrying these mutations. Distinguishing clinico-pathologic features of mut B...