Morning blue light can advance the melatonin rhythm in mild delayed sleep phase syndrome

Morning blue light can advance the melatonin rhythm in mild delayed sleep phase syndrome
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DOI:
10.1111/j.1479-8425.2006.00250.x
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发表时间:
2007-01-01
影响因子:
1.1
通讯作者:
Kemp, Kristyn
Kemp, Kristyn
中科院分区:
医学4区
文献类型:
--
作者:
Lack, Leon;Bramwell, Toby;Kemp, Kristyn

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我们研究了早晨蓝光对轻度睡眠相延迟综合征患者的睡眠和褪黑激素节律的影响。参与者(n=18)被随机分配到光照组或对照组。在一周的时间里,起床时间逐渐提前到06:00小时,在此期间,亮光组也在醒来后立即接受了两个小时的蓝光。与对照组相比,蓝光组的暗光褪黑素的开始时间显著提前2.53小时。然而,在治疗后,两组患者的睡眠时间都没有显著增加。有效的睡眠延迟综合症治疗可能需要辅助的行为指导。
We investigated the effectiveness of morning blue light in advancing the sleep and melatonin rhythm of individuals with mild delayed sleep phase syndrome. The participants (n = 18) were randomly allocated to a light or control group. Wake-up times were gradually advanced to 06:00 hours over a week, during which the light group also received two hours of blue light immediately after waking. The blue light group showed a significant 2.53-h advance of dim light melatonin onset, compared to no change in the control group. However, neither group had a significant advance of sleep times following treatment. Effective delayed sleep phase syndrome treatment may require adjunct behavioral instructions.