Validation of the Edinburgh Depression Scale during pregnancy
Validation of the Edinburgh Depression Scale during pregnancy
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DOI：
10.1016/j.jpsychores.2010.07.008
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发表时间：
2011-04-01
影响因子：
4.7
通讯作者：
Pop, Victor
中科院分区：
文献类型：
--
作者：
Bergink, Veerle;Kooistra, Libbe;Pop, Victor
背景：妊娠期抑郁症未经治疗可能会对母亲和孩子产生不良后果。因此，建议在一般怀孕人群中进行抑郁症筛查。爱丁堡抑郁量表（EDS）被广泛用于产后抑郁症筛查。对于怀孕期间使用哪个EDS截止值没有共识。本研究的目的是检查EDS的预测有效性和同期有效性的所有三个孕期。方法：在845例孕妇的大样本中，评价EDS的敏感性、特异性和有效性。综合国际诊断访谈（抑郁模块）被用来检查EDS的预测效度。采用症状自评量表（SCL-90）的焦虑和躯体化分量表检验其同时效度。只有患有严重抑郁症的女性才被视为病例。结果：抑郁症患病率随时间的推移而下降，分别为5.6%、5.4%和3.4%。EDS评分在期末下降，而SCL-90焦虑分量表评分在期末上升。EDS与SCL-90焦虑、躯体化分量表具有较高的重测信度和同时效度。受试者工作特征曲线下面积较高，在0.93和0.97之间变化。第一个三个月的截止值为11，第二个三个月和第三个三个月的截止值为10，给出了最适当的敏感性、特异性和阳性预测值的组合。结论：EDS是筛查妊娠期抑郁症的可靠工具。建议采用比产后期间常用的更低的临界值。(c)2011 Elsevier Inc. All rights reserved.
Background: Untreated depression during pregnancy may have adverse outcomes for the mother and her child. Screening for depression in the general pregnant population is thus recommended. The Edinburgh Depression Scale (EDS) is widely used for postpartum depression screening. There is no consensus on which EDS cutoff values to use during pregnancy. The aim of the current study was to examine the predictive validity and concurrent validity of the EDS for all three trimesters of pregnancy. Methods: In a large unselected sample of 845 pregnant women, the sensitivity, specificity, and validity of the EDS were evaluated. The Composite International Diagnostic Interview (depression module) was used to examine the predictive validity of the EDS. The anxiety and somatization subscales of the Symptom Checklist 90 (SCL-90) were used to examine its concurrent validity. Only women with a major depressive episode were considered as cases. Results: The prevalence of depression decreased toward end term: 5.6%, 5.4%, and 3.4%. The EDS scores also decreased toward end term, while the SCL-90 subscale anxiety scores increased. The EDS showed high test-retest reliability and high concurrent validity with the SCL-90 anxiety and somatization subscales. The area under the receiver operating characteristic curve was high and varied between 0.93 and 0.97. A cutoff value of 11 in the first trimester and that of 10 in the second and third trimesters gave the most adequate combination of sensitivity, specificity, and positive predictive value. Conclusions: The EDS is a reliable instrument for screening depression during pregnancy. A lower cutoff than commonly applied in the postpartum period is recommended. (c) 2011 Elsevier Inc. All rights reserved.