Literature review: Supplemented phase diagram of the trehalose-water binary mixture
Literature review: Supplemented phase diagram of the trehalose-water binary mixture
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DOI：
10.1006/cryo.2000.2244
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发表时间：
2000-05-01
期刊：
影响因子：
2.7
通讯作者：
Toner, M
中科院分区：
文献类型：
--
作者：
Chen, TN;Fowler, A;Toner, M
海藻糖在许多领域都有很大的应用价值，包括冷冻干燥、冷冻保护和脱水生物。虽然海藻糖-水补充相图的数据以前曾出现在文献中，但这些数据广泛分散，并以几个单位进行报告。在本研究中，收集并分析了海藻糖-水二元体系的文献数据。文献数据被发现是相当一致的，在水、海藻糖和二水海藻糖的熔点以及水的玻璃化转变温度方面基本一致。溶解度、冻结和玻璃化转变曲线也有很好的一致性。然而，对于纯海藻糖的玻璃化转变温度并没有达成一致意见。此外，用Gordon-Taylor方程模拟了海藻糖-水的玻璃化转变曲线，k值为5.2。本报告中收集的数据将对进一步研究海藻糖的保护能力有很大的帮助。(C)2000年学术出版社。
Trehalose is of great interest in many fields, including freeze-drying, cryoprotection, and anhydrobiosis. Although data for the trehalose-water supplemented phase diagram have previously appeared in the literature, the data have been widely scattered and reported in several units. In this study, literature data for the binary trehalose-water system were collected and analyzed. The literature data were found to be reasonably consistent, with substantial agreement on the melting points for water, trehalose, and trehalose dihydrate and the glass transition temperature of water. There was also good agreement for the solubility, freezing, and glass transition curves. However, there was no general agreement on the glass transition temperature of pure trehalose. Additionally, the trehalose-water glass transition curve was modeled using the Gordon-Taylor equation, with a value for k of 5.2. The collected data in this report will be of much use in further studies of the protective abilities of trehalose. (C) 2000 Academic Press.