Carbon Dots Synthesized from Cinchona Pubescens Vahl. An Efficient Antibacterial Nanomaterial and Bacterial Detector.
Carbon Dots Synthesized from Cinchona Pubescens Vahl. An Efficient Antibacterial Nanomaterial and Bacterial Detector.
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DOI：
10.1002/slct.202104530
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发表时间：
2022-05-06
期刊：
影响因子：
2.1
通讯作者：
Estevez, Miriam
中科院分区：
文献类型：
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作者：
Alexis Gonzalez-Reyna, Marlen;Liliana Espana-Sanchez, Beatriz;Estevez, Miriam
利用水热法合成的毛金鸡纳碳量子点（CD）显示出蓝色发射辐射、pH依赖性、均匀的尺寸、在水中的胶体稳定性和抗菌特性。它们由氧化石墨烯和还原的氧化石墨烯组成，这归因于从同时合成和还原氧化石墨烯的金鸡纳提取的抗氧化剂物质。它们对革兰氏阳性金黄色葡萄球菌和革兰氏阴性铜绿假单胞菌菌株的细菌最小抑菌浓度达到62.5 μ g mL（-1），这优于传统抗生素和从类似天然来源和方法获得的其他CD。光致发光CD还用于检测细菌，这是微生物学、生物技术、医疗诊断和食品安全中的重要应用，显示出区分革兰氏阳性和革兰氏阴性菌株以及死的和活的革兰氏阳性细菌的能力。因此，由绿色资源获得的CD代表了生产功能性抗菌剂和细菌检测器的有希望的平台。
Carbon dots (CDs) synthesized using Cinchona pubescens Vahl from the hydrothermal method displayed blue emission radiation, pH dependency, homogeneous sizes, colloidal stability in water, and antibacterial features. They consist of graphene oxide and reduced graphene oxide, attributed to the antioxidant species extracted from the Cinchona pubescens Vahl that simultaneously synthesized and reduced graphene oxide. They reach a bacterial minimal inhibitory concentration of 62.5 mu g mL(-1) against Gram-positive Staphylococcus aureus and Gram-negative Pseudomonas aeruginosa strains, which is better than traditional antibiotics and other CDs obtained from similar natural sources and methods. The photoluminescent CDs were also used to detect bacteria, an essential application in microbiology, biotechnology, medical diagnosis, and food safety, showing the capability of distinguishing between gram-positive and gram-negative strains and between dead and alive gram-positive bacteria. Thus, CDs obtained by green resources represent a promising platform to produce functional antibacterial agents and bacteria detectors.