A new route to sulfonamides via intermolecular radical addition to pentafluorophenyl vinylsulfonate and subsequent aminolysis
A new route to sulfonamides via intermolecular radical addition to pentafluorophenyl vinylsulfonate and subsequent aminolysis
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DOI：
10.1021/ol026181m
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发表时间：
2002-07-25
期刊：
影响因子：
5.2
通讯作者：
Judd, DB
中科院分区：
文献类型：
--
作者：
Caddick, S;Wilden, JD;Judd, DB
由相应的碘代或溴代化合物和三正丁基氢化锡产生的各种自由基物质以分子间方式添加到活化的受体乙烯基磺酸五氟苯基酯中。然后将每个反应的产物用各种不同的胺进行氨解。
[GRAPHICS]Various radical species generated from either the corresponding iodo- or bromo- compounds and tri-n-butyltin hydride were added in an intermolecular fashion to the activated acceptor pentafluorophenyl vinylsulfonate. The products of each reaction were then subjected to aminolysis with a variety of different amines.