RNA folding and large N matrix theory
RNA folding and large N matrix theory
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DOI：
10.1016/s0550-3213(01)00522-3
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发表时间：
2002-01-14
影响因子：
2.8
通讯作者：
Zee, A
中科院分区：
文献类型：
--
作者：
Orland, H;Zee, A
我们将RNA折叠问题表述为一个N × N矩阵场理论。这种矩阵形式使我们能够根据配分函数的拓扑特征对它们进行系统的分类。这个理论是这样建立的，极限N ->无穷大产生所谓的二级结构（哈特里理论）。通过计算配分函数的1/N-2修正得到三级结构和伪节。我们提出了哈特里递推关系的推广，以生成三级结构。(C) 2002年Elsevier Science B.V.出版
We formulate the RNA folding problem as an N x N matrix field theory. This matrix formalism allows us to give a systematic classification of the terms in the partition function according to their topological character. The theory is set up in such a way that the limit N --> infinity yields the so-called secondary structure (Hartree theory). Tertiary structure and pseudo-knots are obtained by calculating the 1/N-2 corrections to the partition function. We propose a generalization of the Hartree recursion relation to generate the tertiary structure. (C) 2002 Published by Elsevier Science B.V.