The clinical outcomes after complete surgical resection of intramedullary cavernous angiomas: changes in motor and sensory symptoms
The clinical outcomes after complete surgical resection of intramedullary cavernous angiomas: changes in motor and sensory symptoms
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DOI：
10.1038/sc.2008.89
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发表时间：
2009-02-01
期刊：
影响因子：
2.2
通讯作者：
Chung, C. K.
中科院分区：
文献类型：
--
作者：
Park, S. B.;Jahng, T-A;Chung, C. K.
研究设计：脊髓髓内海绵状血管瘤（CAs. Objective：To assess the sensory and motor deficits in the clinical symptoms of patients with immunodeficiency spinal cord cavernous angiomas（CAs）.Objectives：To assess the sensory and motor deficits in the clinical symptoms of patients with immunodeficiency CAs after complete surgery ect.Setting：首尔国立大学医院，韩国.Methods：作者回顾了1995年至2006年期间接受手术切除的14例脊髓髓内CAs患者。平均随访时间为55.0 ± 45.1个月。为分析患者术后症状的变化，ASIA（美国脊髓损伤协会）和乔亚（日本骨科协会）评分系统在不同的时间点使用：术前，术后和最后随访期间。与术前评分相比，随访时患者的平均ASIA评分增加（97.2 +/- 5.3 vs 95.2 +/- 7.6，P = 0.201），但该差异不显著。与术前评分相比，随访时平均乔亚运动评分略有增加（7.2 +/- 1.3 vs 6.8 +/- 1.3，P = 0.107）。患者的术前和随访乔亚感觉评分之间存在显著差异（4.3 +/- 1.0 vs 4.9 +/- 0.9，P = 0.007）。运动功能和感觉功能的完全恢复率分别为45.5%（5/11）和7.1%（1/14）。结论：髓内CA的完全手术切除虽然能改善临床症状，但感觉功能障碍仍存在于完全切除后的较长时间内。
Study design: Evaluation of the surgical effects of patients with intramedullary spinal cord cavernous angiomas (CAs).Objectives: To assess the sensory and motor deficits in the clinical symptoms of patients with intramedullary CAs after complete surgical resection.Setting: Seoul National University Hospital, Korea.Methods: The authors reviewed 14 patients with intramedullary spinal cord CAs who underwent surgical resection between 1995 and 2006. The average follow-up duration was 55.0 +/- 45.1 months. To analyze the changes in the patients' symptoms after surgery, the ASIA (American Spinal Injury Association) and JOA (Japanese Orthopedic Association) scoring systems were used at different time points: preoperative, postoperative and during the final follow-up period.Results: The patients' mean ASIA score at follow-up was increased in comparison to the preoperative score (97.2 +/- 5.3 vs 95.2 +/- 7.6, P = 0.201), but this difference was not significant. The mean JOA motor score at follow-up was slightly increased in comparison to the preoperative score (7.2 +/- 1.3 vs 6.8 +/- 1.3, P = 0.107). There was a significant difference between the patients' preoperative and follow-up JOA sensory score (4.3 +/- 1.0 vs 4.9 +/- 0.9, P = 0.007). The rates of complete resolution of motor and sensory deficits were 45.5% (5/11 patients) and 7.1% (1/14 patients), respectively.Conclusion: Although complete surgical resection could improve the clinical symptoms of intramedullary CAs, the sensory deficits usually remain in the long-term period after complete resection.