Arabidopsis calcium-binding mitochondrial carrier proteins as potential facilitators of mitochondrial ATP-import and plastid SAM-import
Arabidopsis calcium-binding mitochondrial carrier proteins as potential facilitators of mitochondrial ATP-import and plastid SAM-import
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DOI：
10.1016/j.febslet.2011.10.039
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发表时间：
2011-12-15
期刊：
影响因子：
3.5
通讯作者：
Teige, Markus
中科院分区：
文献类型：
--
作者：
Stael, Simon;Rocha, Agostinho G.;Teige, Markus
叶绿体和线粒体是植物重要的细胞过程的核心，并有助于整个代谢途径。钙离子作为细胞器内和周围的第二信使的使用越来越被认为是植物细胞信号传导的重要介质，使植物能够发育或适应不断变化的环境条件。在这里，我们研究了四个钙依赖的线粒体载体，在拟南芥基因组中编码。一个未知的基板载体，这是以前发现本地化叶绿体，提出了一个钙依赖性的S-腺苷甲硫氨酸载体。对于三个预测的ATP/磷酸盐载体，我们提出的实验证据表明，它们可以作为线粒体ATP进口商。(C)2011年欧洲生物化学学会联合会。由Elsevier B出版。V.保留所有权利。
Chloroplasts and mitochondria are central to crucial cellular processes in plants and contribute to a whole range of metabolic pathways. The use of calcium ions as a secondary messenger in and around organelles is increasingly appreciated as an important mediator of plant cell signaling, enabling plants to develop or to acclimatize to changing environmental conditions. Here, we have studied the four calcium-dependent mitochondrial carriers that are encoded in the Arabidopsis genome. An unknown substrate carrier, which was previously found to localize to chloroplasts, is proposed to present a calcium-dependent S-adenosyl methionine carrier. For three predicted ATP/phosphate carriers, we present experimental evidence that they can function as mitochondrial ATP-importers. (C) 2011 Federation of European Biochemical Societies. Published by Elsevier B. V. All rights reserved.