Simulation of flow in an exact replica of a diseased human carotid artery
Simulation of flow in an exact replica of a diseased human carotid artery
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DOI：
10.1016/j.apm.2006.10.026
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发表时间：
2007-11-01
影响因子：
5
通讯作者：
Weigand, B.
中科院分区：
文献类型：
--
作者：
Younis, B. A.;Spring, S.;Weigand, B.
我们报告了正在进行的努力的结果，旨在开发一个计算模型的血流在患病的人颈动脉。最近对实际病变动脉的精确复制品中的流动进行的可视化显示，存在复杂的三维流动结构，其特征是多个回流区，并在内外动脉中形成不稳定的喷流。即使动脉入口的流动条件保持稳定，实验表明，由此产生的入口下游的流动是不稳定的和混沌的。目前的计算旨在确定是否可以用一个实用的有限体积计算模型来捕捉这种行为，并检查空间和时间分辨率对模拟质量的影响。(C)2006 Elsevier Inc.保留所有权利。
We report on results of ongoing efforts directed towards the development of a computational model for flow in diseased human carotid arteries. Recent visualizations of the flow in an exact replica of an actual diseased artery have revealed the presence of complex, three-dimensional flow structures characterized by multiple recirculation zones and the formation of unstable jets in both the internal and external arteries. Even though the flow conditions at inlet to the artery were kept steady, the experiments showed that the resulting flow downstream of the inlet was unsteady and chaotic. The present computations aim to determine whether such behavior can be captured with a practical finite-volume computational model, and to examine the impact of spatial and temporal resolution on the quality of simulations. (c) 2006 Elsevier Inc. All rights reserved.