I2/TBPB Mediated Oxidative Reaction of N-Tosylhydrazones with Anilines: Practical Construction of 1,4-Disubstituted 1,2,3-Triazoles under Metal-Free and Azide-Free Conditions
I2/TBPB Mediated Oxidative Reaction of N-Tosylhydrazones with Anilines: Practical Construction of 1,4-Disubstituted 1,2,3-Triazoles under Metal-Free and Azide-Free Conditions
复制标题
I-2/TBPB 介导的 N-甲苯磺酰腙与苯胺的氧化反应：在无金属和无叠氮条件下实际构建 1,4-二取代 1,2,3-三唑
DOI：
10.1021/ol502431b
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发表时间：
2014-10-03
期刊：
影响因子：
5.2
通讯作者：
Ji, Shun-Jun
中科院分区：
文献类型：
--
作者：
Cai, Zhong-Jian;Lu, Xin-Mou;Ji, Shun-Jun
An efficient I-2 (20 mol %)/TBPB mediated oxidative formal [4 + 1] cycloaddition of N-tosylhydrazones with anilines via C-N/N-N bond formation and S-N cleavage has been developed. This protocol represents a simple, general, and efficient approach for the construction of 1,2,3-triazoles under metal-free and azide-free conditions by utilizing a catalytic amount of I-2.
