MAGNETIC-RESONANCE-IMAGING OF BRAIN-TUMORS
MAGNETIC-RESONANCE-IMAGING OF BRAIN-TUMORS
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DOI：
10.1055/s-2008-1041445
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发表时间：
1986-03-01
影响因子：
2.7
通讯作者：
SORY, WC
中科院分区：
文献类型：
--
作者：
MARAVILLA, KR;SORY, WC
十多年前，随着计算机断层扫描(CT)的引入，检测和诊断脑肿瘤的能力经历了重大的进步。然而，由于CT在评估脑部病变方面的非特异性，术前对肿瘤的组织学诊断仍然是一个难以实现的目标。磁共振成像(MRI)被誉为中枢神经系统(CNS)诊断成像的下一个重大进展。该技术通过分析各种病变发出的磁共振信号，有望提高诊断能力。然而，这一假设目前仍未得到证实，MRI技术还需要更多的研究，特别是在光谱学领域，才能确定这一希望是否以及在多大程度上将成为现实。MRI对组织的准确诊断尚未成为现实，尽管如此，作为一种临床影像手段，MRI在检测颅内异常方面已经被证明比CT更敏感。在中枢神经系统肿瘤中，MRI能更好地评估脑内浸润性肿瘤的完整范围。MRI能够在轴向、冠状位和矢状位获得高分辨率、高对比度的脑部图像，从而能够对病变进行三维评估，并更准确地估计其体积及其相对于大脑内关键解剖结构的准确位置。此外，随着经验的积累，诊断特定病变的标准将更加精确。基于上述原因，与单独使用CT相比，MRI能够提供更多有关颅内异常的信息。反过来，这将使更好的治疗计划成为可能。此外，由于没有电离辐射，也没有静脉注射造影剂，MRI应该被认为是患者术后和治疗后随访的首选方法，以评估治疗效果。
The ability to detect and diagnose brain tumors underwent a major advance with the introduction of computed tomography (CT) shortly over a decade ago. However, the preoperative, histologic diagnosis of tumors has remained an elusive goal because of the nonspecificity of CT in evaluating brain lesions. Magnetic resonance imaging (MRI) has been hailed as the next major advance in diagnostic imaging of the central nervous system (CNS). The technique offers the promise of improved diagnostic ability through analysis of the magnetic resonance signal emitted by various lesions. However, that hypothesis remains unproved at the present time and considerably more research is needed in MRI technology, especially in the area of spectroscopy, before it can be determined whether, and to what degree, this hope will be realized.Precise tissue diagnosis by MRI is not yet a reality; nonetheless, as a clinical imaging modality, MRI has already proved to be more sensitive than CT for detection of intracranial abnormalities. In CNS neoplasms, MRI is better able to assess the full extent of an infiltrating tumor within the brain. The capability of MRI for obtaining high-resolution, high-contrast images of the brain in axial, coronal, and sagittal orientations allows for three-dimensional assessment of a lesion and a more accurate estimate of its volume and its precise location relative to critical anatomic structures within the brain. Furthermore, as more experience is gained, more precise criteria will be developed for diagnosis of specific lesions. For the foregoing reasons, MRI is able to provide more information about an intracranial abnormality than is possible using CT alone. This, in turn, should enable better treatment planning. Also, since there is no ionizing radiation and no intravenous injection of contrast, MRI should be considered the procedure of choice in postoperative and post-treatment follow-up of patients for evaluating therapeutic response.