RISK-FACTORS FOR SMALL-FOR-GESTATIONAL-AGE BIRTH IN A PRETERM POPULATION
RISK-FACTORS FOR SMALL-FOR-GESTATIONAL-AGE BIRTH IN A PRETERM POPULATION
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DOI：
10.1016/0002-9378(92)91607-c
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发表时间：
1992-05-01
影响因子：
9.8
通讯作者：
LIEBERMAN, E
中科院分区：
文献类型：
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作者：
LANG, JM;COHEN, A;LIEBERMAN, E
目的：本研究的目的是发现任何明显的危险因素为小于胎龄儿出生早产儿。研究设计：人口统计学和产科危险因素进行了比较，为136小于胎龄儿早产儿和636适当的胎龄儿早产儿。结果：三个显着的危险因素，早产儿生长迟缓被发现：黑人母系（比值比2.2; 95%置信区间（1.4至3.5）;母体毒血症（比值比3.2; 95%置信区间1.7至6.1）;以及低母体体重增加（比值比4.0; 95%置信区间1.8至8.8）或缺失母亲体重增加的信息，这可能是产前护理晚或无产前护理的标志（比值比4.9; 95%置信区间1.9至12.6）。 产妇吸烟率相似的小和适当的胎龄组（42%和43%，分别）。结论：毒血症，体重增加，和种族是早产儿和足月人群中小于胎龄儿出生的可能危险因素;在已经高风险的早产儿领域，产妇吸烟似乎并没有增加小于胎龄儿出生的风险。
OBJECTIVE: The objective of this study was to discover any distinct risk factors for small-for-gestational-age birth among premature infants.STUDY DESIGN: Demographic and obstetric risk factors were compared for 136 small-for-gestational-age prematures and 636 appropriate-for-gestational-age premature infants.RESULTS: Three significant risk factors for growth retardation among premature infants were found: black maternal race (odds ratio 2.2; 95% confidence interval (1.4 to 3.5); maternal toxemia (odds ratio 3.2; 95% confidence interval 1.7 to 6.1); and either low maternal weight gain (odds ratio 4.0; 95% confidence interval 1.8 to 8.8) or missing information on maternal weight gain, which could be a marker for late or no prenatal care (odds ratio 4.9; 95% confidence interval 1.9 to 12.6). Maternal smoking rates were similar in the small- and appropriate-for-gestational-age groups (42% and 43%, respectively).CONCLUSIONS: Toxemia, weight gain, and race are likely risk factors for small-for-gestational-age birth in both preterm and term populations; within the already high-risk domain of prematurity, maternal smoking did not appear to confer added risk for small-for-gestational-age birth.