Cerebral activation during anal and rectal stimulation
Cerebral activation during anal and rectal stimulation
复制标题
DOI：
10.1006/nimg.2001.0901
复制
发表时间：
2001-11-01
期刊：
影响因子：
5.7
通讯作者：
Enck, P
中科院分区：
文献类型：
--
作者：
Lotze, M;Wietek, B;Enck, P
直肠受内脏传入神经支配，而肛管则受体感阴部神经支配。人脑中肠道感觉的这两个中心区域的表征很大程度上是未知的。使用事件相关功能磁共振成像 (fMRI) 对八名健康受试者进行肛管和远端直肠的无痛气动刺激。主观感觉尺度显示，两种刺激期间的不愉快和疼痛没有差异。两种类型的刺激均显示次级体感、岛叶、扣带回、左顶下叶和右眶额皮质中的 MM 激活。肛门刺激导致初级感觉和运动皮层、辅助运动区和左侧小脑的额外激活。我们得出的结论是，内脏直肠刺激和体感肛门刺激的主要区别在于它们的初级感觉激活和运动区域的额外激活。厌恶性体感刺激后的这种运动反应可能是由反射性回避反应引起的，而在更分散的内脏刺激后观察不到这种反应。 (C) 2001 年学术出版社。
While the rectum is innervated by visceral afferents, the anal canal is innervated by the somatosensory pudendal nerve. The representation of these two central domains of intestinal sensations in the human brain is largely unknown. Nonpainful pneumatic stimulation of the anal canal and the distal rectum using event-related functional magnetic resonance imaging (fMRI) was performed in eight healthy subjects. Subjective scaling of sensations revealed no differences in unpleasantness and pain during both stimuli. Both types of stimuli revealed MM activation in secondary somatosensory, insula, cingular gyrus, left inferior parietal, and right orbitofrontal cortex. Anal stimulation resulted in additional activation of primary sensory and motor cortex, supplementary motor area, and left cerebellum. We concluded that viscerorectal and somatosensory anal stimulation predominantly differ in their primary sensory activation and additional activation in motor areas. This motor response following aversive somatosensory stimuli may be caused by a reflexive avoidance reaction which is not observed after the more diffuse experienced visceral stimulation. (C) 2001 Academic Press.