Theta-Modulated Input Reduces Intrinsic Gamma Oscillations in a Hippocampal Model.
Theta-Modulated Input Reduces Intrinsic Gamma Oscillations in a Hippocampal Model.
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Theta 调制输入减少海马模型中的固有伽马振荡。
DOI：
10.1016/j.neucom.2006.10.086
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发表时间：
2007
期刊：
影响因子：
6
通讯作者：
Levy,WilliamB
中科院分区：
文献类型：
--
作者：
Hocking,AshlieB;Levy,WilliamB
将θ调制输入引入海马CA3区的最小模型对伽马振荡具有显著影响。在没有θ调制输入的情况下，伽马振荡在参数范围内是鲁棒的。引入θ调制输入减弱了伽马振荡的功率更符合从实验室动物获得的功率谱。通过这些变化，海马模型的模拟能够再现清醒小鼠中测量的海马功率谱。
Introducing theta-modulated input into a minimal model of the CA3 region of the hippocampus has significant effects on gamma oscillations. In the absence of theta-modulated input, the gamma oscillations are robust across a range of parameters. Introducing theta-modulated input weakens the gamma oscillations to a power more consistent with power spectra acquired from laboratory animals. With these changes, simulations of the hippocampal model are able to reproduce hippocampal power spectra measured in awake mice.