Physiology and pathophysiology of respiratory mucosa of the nose and the paranasal sinuses.
Physiology and pathophysiology of respiratory mucosa of the nose and the paranasal sinuses.
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DOI：
10.3205/cto000071
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发表时间：
2010
期刊：
影响因子：
--
通讯作者：
Beule AG
中科院分区：
文献类型：
--
作者：
Beule AG
本文就鼻及鼻窦呼吸道粘膜的解剖生理及其临床意义作一综述。解释了鼻内清洁的基础知识，包括粘膜纤毛清除和鼻反射，以及防御机制。生理伤口愈合，鼻内局部药物治疗和典型的诊断程序，以评估呼吸功能的方面。最后，不同亚型的非过敏性鼻炎的病理生理学概述与治疗建议。
In this review, anatomy and physiology of the respiratory mucosa of nose and paranasal sinuses are summarized under the aspect of its clinical significance. Basics of endonasal cleaning including mucociliary clearance and nasal reflexes, as well as defence mechanisms are explained. Physiological wound healing, aspects of endonasal topical medical therapy and typical diagnostic procedures to evaluate the respiratory functions are presented. Finally, the pathophysiologies of different subtypes of non-allergic rhinitis are outlined together with treatment recommendations.