COEXISTENCE OF CHOLECYSTOKININ-LIKE AND SUBSTANCE P-LIKE PEPTIDES IN NEURONS OF THE DORSAL ROOT-GANGLIA OF THE RAT
COEXISTENCE OF CHOLECYSTOKININ-LIKE AND SUBSTANCE P-LIKE PEPTIDES IN NEURONS OF THE DORSAL ROOT-GANGLIA OF THE RAT
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DOI：
10.1016/0304-3940(82)90244-0
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发表时间：
1982-01-01
影响因子：
2.5
通讯作者：
CUELLO, AC
中科院分区：
文献类型：
--
作者：
DALSGAARD, CJ;VINCENT, SR;CUELLO, AC
采用抗胆囊收缩素和P物质的间接免疫组化技术，对正常和秋水仙碱处理的大鼠脊髓背角和背根神经节进行了研究。在脊髓中，在背角的浅层中观察到类似的P物质和胆囊收缩素阳性网络的分布。秋水仙碱处理后大鼠背根神经节内可见数个胆囊收缩素和P物质免疫反应细胞体。对先前胆囊收缩素染色的切片进行P物质洗脱和保留后，所有胆囊收缩素阳性细胞也具有P物质样免疫反应性，反之亦然。
Using the indirect immunohistochemical technique with antisera to cholecystokinin and to substance P, the spinal dorsal horn and dorsal root ganglia of normal and colchicine-treated rats were studied. In the spinal cord, a similar distribution of substance P- and cholecystokinin-positive networks in the superficial layers of the dorsal horn was observed. In the dorsal root ganglia, several cholecystokinin and substance P immunoreactive cell bodies were seen in colchicine-treated rats. After elution and restaining for substance P, of sections previously stained for cholecystokinin, all cholecystokinin-positive cells also contained substance P-like immunoreactivity and vice versa.