Reduction of Exit-Site Infections in Peritoneal Dialysis by Local Application of Metallic Silver: A Preliminary Report
Reduction of Exit-Site Infections in Peritoneal Dialysis by Local Application of Metallic Silver: A Preliminary Report
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通过局部应用金属银减少腹膜透析出口部位感染：初步报告
DOI：
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发表时间：
1994
影响因子：
2.8
通讯作者：
G. Gahl
中科院分区：
文献类型：
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作者：
Andreas A. Kahl;C. Grosse;K. Kahl;H. Becker;T. Leimbach;Jutta Wagner;G. Gahl
出口部位感染（ESl）和慢性ESl尤其是腹膜透析（PD）治疗的并发症，可导致隧道感染（TI）、腹膜炎和移除PD导管。在Piraino等人的一项研究中（1）52根需要取出的腹膜透析导管中有65%发生了ESl和TI。为了减少持续性非卧床腹膜透析（CAPD）程序的ESI速率修改（例如，非断开系统）（2），研究了不同的CAPD导管构造和材料（参见，例如，参考文献3-5）。Luzaret等人表明，出口部位护理的改善降低了ESI率（6）。然而，尚未获得有效和持久的预防ESLs。银的抗微生物作用已被注意到多年（7），并且仍然用于预防（8-10）和治疗（11）感染。本研究的目的是确定预防性应用银是否可以减少CAPD中的ESLs。
Exit-site infections (ESls) and chronic ESls in particular are complications of peritoneal dialysis (PD) therapy that can lead to tunnel infection (TI), peritonitis, and removal of the PD catheter. In a study by Piraino et al. (1) ESls and TIs occurred in 65% of the 52 PD catheters that required removal. To reduce ESI rate modifications of the continuous ambulatory peritoneal dialysis (CAPD) procedure (e.g., nondisconnect systems) (2), different CAPD catheter configurations and materials were investigated (see, e.g., References 3-5). Luzaret al. showed that improved care of the exit site reduces the ESI rate (6). However, effective and long-Iasting prevention of ESls has not yet been obtained. The antimicrobial effect of silver has been noted for many years (7) and is still used for prophylaxis (8-10) and therapy (11) of infections. The aim of this study was to determine whether ESls in CAPD could be reduced by the prophylactic application of silver .