Impact of an Antibiotic Stewardship Program on Antibiotic Prescription for Acute Respiratory Tract Infections in Children: A Prospective Before-After Study
Impact of an Antibiotic Stewardship Program on Antibiotic Prescription for Acute Respiratory Tract Infections in Children: A Prospective Before-After Study
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DOI：
10.1177/0009922819870248
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发表时间：
2019-08-20
影响因子：
1.6
通讯作者：
Apiwattanakul, Nopporn
中科院分区：
文献类型：
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作者：
Aoybamroong, Nalinee;Kantamalee, Worawit;Apiwattanakul, Nopporn
我们评估了抗生素管理计划（ASP）对医学院急性呼吸道感染（阿尔蒂）抗生素处方的有效性。我们的ASP包括通过电子邮件和LINE（一种即时通讯应用程序）向教职员工、研究员和住院医生提供抗生素使用指南，并在检查室张贴指南。对诊断为阿尔蒂的儿科患者的病历进行审查，以评估抗生素处方的适当性。ASP可以将适当率从78%（2553次访问中的1979次）提高到83.4%（2935次访问中的2449次; P <0.001）。居民（95%）的适当性基线高于研究员（82%）和教职员工（75%）。ASP仅显著提高了教职员工的适当性，特别是在半私人诊所（75%至83%，P <0.001）。总之，我们的ASP增加了阿尔蒂抗生素处方的适当性，在半私人诊所的教职员工中影响最大。
We assessed the effectiveness of an antibiotic stewardship program (ASP) on antibiotic prescriptions for acute respiratory tract infection (ARTI) in a medical school. Our ASP included delivering an antibiotic use guideline via e-mail and LINE (an instant messaging app) to faculty staff, fellows, and residents, and posting of the guideline in examination rooms. Medical records of pediatric patients diagnosed with ARTI were reviewed to assess the appropriateness of antibiotic prescription. ASP could increase the rate of appropriateness from 78% (1979 out of 2553 visits) to 83.4% (2449 out of 2935 visits; P < .001). The baseline of appropriateness was higher in residents (95%) compared with fellows (82%) and faculty staff (75%). The ASP significantly increased the appropriateness only in faculty staff, especially in semiprivate clinics (75% to 83%, P < .001). In conclusion, our ASP increased appropriateness of antibiotic prescriptions for ARTI, with the greatest impact among faculty staff in semiprivate clinics.