Relationship between hyperglycaemia at admission and prognosis in patients with acute myocardial infarction: a retrospective cohort study
Relationship between hyperglycaemia at admission and prognosis in patients with acute myocardial infarction: a retrospective cohort study
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急性心肌梗死患者入院高血糖与预后关系的回顾性队列研究
DOI：
10.1136/pmj-2021-141454
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发表时间：
2022-09
影响因子：
5.1
通讯作者：
Lin Che
中科院分区：
文献类型：
--
作者：
Linlin Liu;Jun Qian;Wenwen Yan;Xuebo Liu;Ya Zhao;Lin Che
背景用于识别急性心肌梗死(AMI)患者高危人群的最佳入院高血糖阈值及其对临床预后的影响尚不清楚。方法回顾性分析“重症监护医学信息集市III”数据库中2001年6月至2012年12月收治的2027例AMI患者。从受试者工作特征（ROC）曲线中获得入院血糖（Glucose_0）预测伴糖尿病和不伴糖尿病的AMI患者住院死亡率的显着临界值，然后根据相应的临界值将患者分为高血糖组和非高血糖组。主要终点是医院和 1 年死亡率。结果 在 2027 名患者中，有 311 名患者死亡（15.3%）。根据 ROC 曲线，糖尿病患者和非糖尿病患者中 Glucose_0 预测医院死亡率的显着临界值分别为 224.5 和 139.5 mg/dL。高血糖亚组的粗住院死亡率和 1 年死亡率高于相应的非高血糖组（p结论）入院时高血糖是 AMI 患者住院期间和 1 年死亡率的独立预测因子，尤其是非糖尿病患者。
BackgroundThe optimal threshold of hyperglycaemia at admission for identifying high-risk individuals in patients with acute myocardial infarction (AMI) and its impact on clinical prognosis are still unclear.MethodsWe retrospectively reviewed 2027 patients with AMI admitted from June 2001 to December 2012 in the ‘Medical Information Mart for Intensive Care III’ database. The significant cut-off values of admission blood glucose (Glucose_0) for predicting hospital mortality in patients with AMI with and without diabetes were obtained from the receiver operating characteristic (ROC) curve, then patients were assigned to hyperglycaemia and non-hyperglycaemia groups based on corresponding cut-off values. The primary endpoints were the hospital and 1-year mortality.ResultsAmong 2027 patients, death occurred in 311 patients (15.3%). According to the ROC curve, the significant cut-off values of Glucose_0 to predict hospital mortality were 224.5 and 139.5 mg/dL in patients with diabetes and without diabetes, respectively. The crude hospital and 1-year mortality of the hyperglycaemia subgroup were higher than the corresponding non-hyperglycaemia group (pConclusionHyperglycaemia at admission was an independent predictor for mortality during hospitalisation and at 1-year in patients with AMI, especially in patients without diabetes.
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影响因子：
3.3
作者：
Łukasz Kalińczuk;K. Zieliński;J. Prȩgowski;J. Przyłuski;M. Karcz;P. Bekta;M. Ciszewski;Z. Dzielińska;A. Witkowski;M. Demkow
通讯作者：
Łukasz Kalińczuk;K. Zieliński;J. Prȩgowski;J. Przyłuski;M. Karcz;P. Bekta;M. Ciszewski;Z. Dzielińska;A. Witkowski;M. Demkow
DOI：
10.1016/j.ajem.2013.10.027
发表时间：
2014
期刊：
The American journal of emergency medicine
影响因子：
--
作者：
G. Koraćević
通讯作者：
G. Koraćević
DOI：
10.36503/chcmj1(1)-03
发表时间：
2004
期刊：
Procedia Engineering
影响因子：
--
作者：
A. Maseri;D. Cianflone
通讯作者：
A. Maseri;D. Cianflone
影响因子：
2.1
作者：
Yuhan Qin;G. Yan;Yong Qiao;Dong Wang;E. Luo;J. Hou;Chengchun Tang
通讯作者：
Yuhan Qin;G. Yan;Yong Qiao;Dong Wang;E. Luo;J. Hou;Chengchun Tang
高入院血糖水平预示非糖尿病急性心肌梗死患者短期临床结果较差：一项回顾性观察研究
影响因子：
2.1
作者：
Ding, Xiao Song;Wu, Shan Shan;Li, Hong Wei
通讯作者：
Li, Hong Wei