Oxidative [4 + 2] annulation of 1-naphthols with alkynes accelerated by an electron-deficient rhodium(<scp>iii</scp>) catalysts
Oxidative [4 + 2] annulation of 1-naphthols with alkynes accelerated by an electron-deficient rhodium(<scp>iii</scp>) catalysts
复制标题
缺电子铑(<scp>iii</scp>)催化剂加速1-萘酚与炔烃的氧化[4 2]成环反应
DOI：
10.1039/d1ob02181h
复制
发表时间：
2022
影响因子：
3.2
通讯作者：
Tanaka Ken
中科院分区：
文献类型：
--
作者：
Araujo Dias Antonio Junio;Takahashi Hiroto;Nogami Juntaro;Nagashima Yuki;Tanaka Ken
1,3-二氧羰基-2,4,5-三甲基环戊二烯（CpE）铑配合物在温和条件下催化1-萘酚与内炔的氧化环化反应中表现出较高的效率。DFT计算表明，较低的金属-去质子化活化能和还原消除步骤是提高反应活性的关键。
The 1,3-diethoxycarbonyl-2,4,5-trimethylcyclopentadienyl (CpE) rhodium(III) complex displayed high efficacy in the catalytic oxidative annulation of 1-naphthols with internal alkynes under mild conditions. DFT calculations revealed that lower activation energies for the concerted metalation-deprotonation and the reductive elimination steps are the key to improved reactivity.