SCIENCE, ART, AND ARTIFACTS - HOW IMPORTANT IS QUANTIFICATION FOR THE PRACTICING PHYSICIAN INTERPRETING MYOCARDIAL PERFUSION STUDIES
SCIENCE, ART, AND ARTIFACTS - HOW IMPORTANT IS QUANTIFICATION FOR THE PRACTICING PHYSICIAN INTERPRETING MYOCARDIAL PERFUSION STUDIES
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DOI：
10.1007/bf03032556
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发表时间：
1994-09-01
影响因子：
2.4
通讯作者：
WACKERS, FJT
中科院分区：
文献类型：
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作者：
WACKERS, FJT
虽然在改进显像剂和成像设备方面已经作出了相当大的努力，但对优化图像解释的因素的关注相对较少。应力心肌灌注图像通常仅通过目视检查来解释。这可能会在观察者之间和观察者内部引入相当大的可变性。重要的是，心肌灌注成像的临床用途可能无法在许多实验室中使用视觉分析一致地再现。显像剂在平面或单光子发射计算机断层图像上的相对心肌分布可以很容易地量化，并通过计算机处理与正常数据文件进行比较。心肌灌注图像的量化提供了灌注异常程度和缺陷可逆性的可重复性测量。灌注异常的程度已被证明具有预后意义。心肌灌注图像的计算机量化不仅提高了总体诊断率，而且提高了解释的可靠性、准确性、置信度和可重复性。
Although considerable efforts have been directed toward improving imaging agents and imaging equipment, relatively little attention has been given to factors that optimize image interpretation. Stress myocardial perfusion images are often interpreted by visual inspection alone. This may introduce considerable inter- and intraobserver variability. Importantly, clinical usefulness of myocardial perfusion imaging may not be consistently reproduced in many laboratories using visual analysis. Relative myocardial distribution of imaging agents on either planar or single-photon emission computed tomographic images can be readily quantified and compared with normal data files by computer processing. Quantification of myocardial perfusion images provides a reproducible measure of the extent of perfusion abnormalities and defect reversibility. The extent of perfusion abnormalities has been shown to have prognostic significance. Computer quantification of myocardial perfusion images improves not only the overall diagnostic yield but also enhances reliability, accuracy, confidence, and reproducibility of interpretation.