Microfabricated planar glass gas chromatography with photoionization detection
Microfabricated planar glass gas chromatography with photoionization detection
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DOI：
10.1016/j.chroma.2009.12.009
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发表时间：
2010-01-29
影响因子：
4.1
通讯作者：
Milton, Martin J. T.
中科院分区：
文献类型：
--
作者：
Lewis, Alastair C.;Hamilton, Jacqueline F.;Milton, Martin J. T.
我们报告了一个微型气相色谱系统的发展，适用于挥发性有机化合物（VOCs）的分离和兼容使用作为一个便携式测量设备。已使用95 × 95 mm Schott B270晶片的氢氟酸蚀刻在玻璃基板内产生对称的半球形通道。随后将两个匹配的玻璃板与对齐的通道冷粘合;玻璃表面的平坦度通过货车德瓦尔斯力产生强粘合。该装置包括气体流体互连、注入区和7.5和1.4 m长。320 μ m内径毛细管。光学显微镜证实毛细管具有完全圆形的通道轮廓。直接柱加热和冷却可以使用电阻加热器和Peltier装置的组合来实现。玻璃的低导热性允许在单个玻璃芯片内实现多个均匀温度区。温度控制在10-200摄氏度的范围内，峰值功率需求约为25 W。将7.5 m毛细管柱静态涂敷2 μ m非极性二甲基聚硅氧烷固定相薄膜。一个标准的FID和一个改进的轻量级100 mW的光电离检测器（PID）耦合到该柱和性能测试的气体混合物的单芳族和单萜物种在百万分之一的浓度水平。低功耗GC-PID装置显示出良好的性能，为一个小的挥发性有机化合物和亚ng检测灵敏度的单芳烃。(C)2009 Elsevier B. V.保留所有权利。
We report the development of a microfabricated gas chromatography system suitable for the separation of volatile organic compounds (VOCs) and compatible with use as a portable measurement device. Hydrofluoric acid etching of 95 x 95 mm Schott B270 wafers has been used to give symmetrical hemispherical channels within a glass substrate. Two matching glass plates were subsequently cold bonded with the channels aligned; the flatness of the glass surfaces resulted in strong bonding through van der Waals forces. The device comprised gas fluidic interconnections, injection zone and 7.5 and 1.4 m long. 320 mu m internal diameter capillaries. Optical microscopy confirmed the capillaries to have fully circular channel profiles. Direct column heating and cooling could be achieved using a combination of resistive heaters and Peltier devices. The low thermal conductivity of glass allowed for multiple uniform temperature zones to be achieved within a single glass chip. Temperature control over the range 10-200 degrees C was achieved with peak power demand of approximately 25 W. The 7.5 m capillary column was static coated with a 2 mu m film of non-polar dimethylpolysiloxane stationary phase. A standard FID and a modified lightweight 100 mW photoionization detector (PID) were coupled to the column and performance tested with gas mixtures of monoaromatic and monoterpene species at the parts per million concentration level. The low power GC-PID device showed good performance for a small set of VOCs and sub ng detection sensitivity to monoaromatics. (C) 2009 Elsevier B.V. All rights reserved.