Association between migraine, lifestyle and socioeconomic factors: a population-based cross-sectional study
Association between migraine, lifestyle and socioeconomic factors: a population-based cross-sectional study
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DOI：
10.1007/s10194-011-0321-9
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发表时间：
2011-04-01
影响因子：
7.4
通讯作者：
Olesen, Jes
中科院分区：
文献类型：
--
作者：
Le, Han;Tfelt-Hansen, Peer;Olesen, Jes
研究偏头痛、生活方式或社会经济因素之间是否存在性别特异性关联。我们区分了先兆偏头痛（MA）和无先兆偏头痛（MO）亚型。2002年，研究人员向居住在丹麦的46,418名双胞胎发送了一份问卷，其中包含诊断偏头痛的有效问题以及生活方式和社会经济因素的问题，其中包括31,865名年龄在20-71岁之间的双胞胎。在偏头痛和其他躯体疾病方面，这对双胞胎是丹麦人口的代表，在本研究中也是这样使用的。患偏头痛的风险增加与受教育程度较低、退休、失业和吸烟显著相关。偏头痛风险的降低与大量体育锻炼和饮酒有显著关系。这些亚型之间的直接比较显示，受教育程度低或每周饮酒的受试者患MA的风险比MO低。与无业或退休受试者相比，MA的风险增加。性别之间的直接比较表明，在受教育程度低、失业或正在学习的研究对象中，男性患偏头痛的风险比女性低。在大量体育锻炼、摄入酒精和体重指数超过25的受试者中，男性的风险比女性高。偏头痛与几种生活方式和社会经济因素有关。大多数联系，如低教育和就业状况可能是由于偏头痛的负面影响，而其他联系，如吸烟是偏头痛的危险因素。
To investigate whether sex-specific associations exist between migraine, lifestyle or socioeconomic factors. We distinguished between the subtypes migraine with aura (MA) and migraine without aura (MO). In 2002, a questionnaire containing validated questions to diagnose migraine and questions on lifestyle and socioeconomic factors was sent to 46,418 twin individuals residing in Denmark. 31,865 twin individuals aged 20-71 were included. The twins are representative of the Danish population with regard to migraine and other somatic diseases and were used as such in the present study. An increased risk of migraine was significantly associated with lower level of schooling and education, retirement, unemployment, and smoking. A decreased risk of migraine was significantly associated with heavy physical exercise and intake of alcohol. Direct comparison between the subtypes showed a decreased risk of MA compared to MO in subjects with low education or weekly intake of alcohol. The risk of MA was increased compared to MO in unemployed or retired subjects. Direct comparison between sexes showed a decreased risk of migraine for men compared to women in subjects who were low educated, unemployed or studying. The risk was increased for men compared to women in subjects with heavy physical exercise, intake of alcohol, and body mass index > 25. Migraine was associated with several lifestyle and socioeconomic factors. Most associations such as low education and employment status were probably due to the negative effects of having migraine while others such as smoking were risk factors for migraine.