Late morbidity following nerve-sparing radical hysterectomy
Late morbidity following nerve-sparing radical hysterectomy
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DOI：
10.1016/j.ygyno.2009.10.061
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发表时间：
2010-03-01
影响因子：
4.7
通讯作者：
Zikan, M.
中科院分区：
文献类型：
--
作者：
Cibula, D.;Velechovska, P.;Zikan, M.
目标.保留神经（NS）改良根治性子宫切除术（RH）的主要目的是改善早期宫颈癌根治术后的生活质量。虽然该手术已经讨论了近30年，但关于晚期发病率的数据有限。本研究的目的是前瞻性评估NS RH前和6个月后患者的发病率，并与不同类型的子宫旁切除术后患者的发病率进行比较。使用20项自我报告问卷前瞻性评估多个参数，重点关注发病率的三个主要方面：膀胱功能、性功能和肛门直肠功能。排除接受辅助放疗的患者。入组的是NS RH（N=32）、C型RH（N=19）和D型RH（N=21）后的女性。治疗后全组有9项指标明显恶化：排便用力（P = 0.03）、排便规律（P=0.0006）、排便次数（P=0.02）、是否需要使用泻药（P
Objectives. Nerve-sparing (NS) modification Of radical hysterectomy (RH) has been developed with the main purpose of improving the quality of life after radical surgical treatment of early-stage cervical cancer. Although the procedure has been discussed for almost 30 years, there are only limited data available on late morbidity. The aim of the Study was to prospectively evaluate the morbidity of patients before and 6 months after NS RH and compare that with the morbidity in patients following different types of parametrectomy Without nerve sparing.Methods. Multiple Parameters were assessed prospectively using 20-item self-reported questionnaire, focusing on three main areas of morbidity: bladder, sexual, and anorectal functions. Excluded were patients treated with adjuvant radiotherapy.Results. Enrolled were women following NS RH (N=32), type C RH (N=19), and type D RH (N=21). Nine parameters significantly deteriorate in the whole group after the treatment: defecation straining (p = 0.03), defecation regularity (p=0.0006), defecation frequency (p=0.02), need to use laxatives (p