INFLUENCE OF PLASMODIUM BERGHEI INFECTION ON SUSCEPTIBILITY TO SALMONELLA INFECTION
INFLUENCE OF PLASMODIUM BERGHEI INFECTION ON SUSCEPTIBILITY TO SALMONELLA INFECTION
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DOI：
10.3181/00379727-120-30661
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发表时间：
1965-01-01
影响因子：
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通讯作者：
HOOK, EW
中科院分区：
文献类型：
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作者：
KAYE, D;MERSELIS, JG;HOOK, EW
同时感染伯氏杆菌和鼠伤寒沙门氏菌的小鼠比单独感染更迅速致死。在同时感染疟疾和沙门氏菌的小鼠和只感染疟疾的小鼠之间，平均红细胞压积没有一致的差异。从死于伯氏杆菌和鼠伤寒沙门氏菌感染的小鼠的脾中发现，每克脾中有超过108个沙门氏菌。因此，存活时间的缩短似乎与沙门氏菌感染的增加有关，而与疟疾的增加无关，因为小鼠死于致死性沙门氏菌感染，但血细胞压积高于小鼠疟疾致死的水平。
Concurrent infection in mice with P. berghei and S. typhimurium was more rapidly fatal than either infection alone. There was no consistent difference in mean hematocrit values between mice with both malaria and salmonella infection and mice with only malaria. Spleens removed from mice dying with P. berghei and S. typhimurium infection demonstrated more than 108 salmonella per gram of spleen. Therefore the decreased survival time seemed to be related to enhancement of salmonella infection and not to enhancement of malaria as the mice died with a lethal salmonella infection but with hemato-crit values above the level at which mouse malaria was fatal.