Reduced Sensory Oscillatory Activity during Rapid Auditory Processing as a Correlate of Language-Learning Impairment.
Reduced Sensory Oscillatory Activity during Rapid Auditory Processing as a Correlate of Language-Learning Impairment.
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DOI：
10.1016/j.jneuroling.2010.09.006
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发表时间：
2011-09
影响因子：
2
通讯作者：
Benasich, April A.
中科院分区：
文献类型：
--
作者：
Heim, Sabine;Friedman, Jennifer Thomas;Keil, Andreas;Benasich, April A.
关键词：
成功的语言习得被假设与在感觉皮层中整合快速呈现的简短声音线索的能力有关。大量的研究表明，这种能力在语言学习障碍（LLI）中受到损害。本研究旨在利用一项大型纵向研究的数据，通过对振荡脑活动的电生理测量来检验快速听觉加工过程中的感觉统合。29名LLI患儿和具有典型语言发育的对照组（n=18）在70毫秒的刺激间隔时间内听对准确语音处理至关重要的双音。孩子们执行异常（第二音音高变化）检测任务，或被动聆听。从64个电极记录脑电图。数据源投影到听觉皮层，并提交小波分析，得到皮层电活动的时频表示。结果显示，在γ波段范围（29-52 Hz）的早期（45-75 ms）振荡的幅度和锁相显著降低，特别是在LLI组，对于音调双重波的第二次刺激。这表明当处理快速序列时，LLI的感觉振荡活动的时间组织发生了改变。
Successful language acquisition has been hypothesized to involve the ability to integrate rapidly presented, brief acoustic cues in sensory cortex. A body of work has suggested that this ability is compromised in language-learning impairment (LLI). The present research aimed to examine sensory integration during rapid auditory processing by means of electrophysiological measures of oscillatory brain activity using data from a larger longitudinal study. Twenty-nine children with LLI and control participants with typical language development (n=18) listened to tone doublets presented at a temporal interval that is essential for accurate speech processing (70-ms interstimulus interval). The children performed a deviant (pitch change of second tone) detection task, or listened passively. The electroencephalogram was recorded from 64 electrodes. Data were source-projected to the auditory cortices and submitted to wavelet analysis, resulting in time-frequency representations of electrocortical activity. Results show significantly reduced amplitude and phase-locking of early (45–75 ms) oscillations in the gamma-band range (29–52 Hz), specifically in the LLI group, for the second stimulus of the tone doublet. This suggests altered temporal organization of sensory oscillatory activity in LLI when processing rapid sequences.
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影响因子：
2.4
作者：
Fox AM;Anderson M;Reid C;Smith T;Bishop DV
通讯作者：
Bishop DV
影响因子：
5.3
作者：
Abrams, Daniel A.;Nicol, Trent;Kraus, Nina
通讯作者：
Kraus, Nina
DOI：
10.1016/0013-4694(94)90094-9
发表时间：
1994-03-01
期刊：
ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY
影响因子：
--
作者：
BERG, P;SCHERG, M
通讯作者：
SCHERG, M
DOI：
10.1523/jneurosci.5242-08.2009
发表时间：
2009-06-17
期刊：
The Journal of neuroscience : the official journal of the Society for Neuroscience
影响因子：
--
作者：
Abrams DA;Nicol T;Zecker S;Kraus N
通讯作者：
Kraus N
影响因子：
2.1
作者：
BYRNE, B
通讯作者：
BYRNE, B