Behavioral activation system deficits predict the six-month course of depression
Behavioral activation system deficits predict the six-month course of depression
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DOI：
10.1016/j.jad.2006.01.012
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发表时间：
2006-04-01
影响因子：
6.6
通讯作者：
Klein, DN
中科院分区：
文献类型：
--
作者：
McFarland, BR;Shankman, SA;Klein, DN
背景：行为激活系统（BAS）缺陷被假设为增加抑郁症的风险。本研究检验了这一假设，即用自我报告和电生理方法测量的BAS缺陷将预测6个月的抑郁症病程。方法：在基线时用Carver和白色[Carver，C.S.，白色，T.L.，1994.行为抑制，行为激活，以及对即将到来的奖励和惩罚的情感反应：BIS/BAS量表。J. Psychol. Soc. 67，319-333.] BIS/BAS量表和静息EEG。他们的抑郁症状的一周一周的过程中进行了评估，6个月后与纵向间隔随访评估（LIFE）。结果：基线自我报告的BAS敏感性预测抑郁症诊断（MDD或恶劣心境）在后续行动中，在后续行动中的MDD症状的数量，平均每周抑郁水平，和时间恢复。在控制了与更差病程相关的基线临床变量后，这些影响持续存在。基线休息脑电图α不对称并没有显着预测抑郁症的过程中。局限性：虽然BAS的敏感性预测随后的抑郁症过程中，我们不能确定它是否发挥了因果关系的作用，在维持depression.Conclusions：较低的自我报告BAS的敏感性预测更糟糕的抑郁症过程中，但脑电图不对称不。(c)2006 Elsevier B.V保留所有权利。
Background: Behavioral activation system (BAS) deficits are hypothesized to increase risk for depression. This study tested the hypothesis that BAS deficits, measured with both self-report and electrophysiological methods, would predict the six-month course of depression.Methods: 67 participants with major depressive disorder (MDD) with or without pre-existing dysthymia were assessed at baseline with Carver and White's [Carver, C.S., White, T.L., 1994. Behavioral inhibition, behavioral activation, and affective responses to impending reward and punishment: the BIS/BAS scales. J. Pers. Soc. Psychol. 67, 319-333.] BIS/BAS scales and resting EEG. The week-by-week course of their depressive symptoms was assessed six months later with the Longitudinal Interval Follow-up Evaluation (LIFE).Results: Baseline self-reported BAS sensitivity predicted depression diagnosis (MDD or dysthymia) at follow-up, number of MDD symptoms at follow-up, average weekly level of depression, and time to recovery. These effects persisted after controlling for baseline clinical variables associated with a worse course. Baseline resting EEG alpha asymmetry did not significantly predict the course of depression.Limitations: Although BAS sensitivity predicted the subsequent course of depression, we cannot determine whether it played a causal role in maintaining depression.Conclusions: Lower self-reported BAS sensitivity predicts a worse course of depression but EEG asymmetries do not. (c) 2006 Elsevier B.V All rights reserved.